The role of IFI16 in regulating PANoptosis and implication in heart diseases
X Chang, B Wang, Y Zhao, B Deng, P Liu… - Cell Death Discovery, 2024 - nature.com
Abstract Interferon Gamma Inducible Protein 16 (IFI16) belongs to the HIN-200 protein family
and is pivotal in immunological responses. Serving as a DNA sensor, IFI16 identifies viral …
and is pivotal in immunological responses. Serving as a DNA sensor, IFI16 identifies viral …
Biological relevance of Cytomegalovirus genetic variability in congenitally and postnatally infected children
G Galitska, M Biolatti, M De Andrea, A Leone… - Journal of Clinical …, 2018 - Elsevier
Background Human cytomegalovirus (HCMV) is the leading cause of congenital infections
resulting in severe morbidity and mortality among infected children. Although the virus is …
resulting in severe morbidity and mortality among infected children. Although the virus is …
Nuclear DNA sensor IFI16 as circulating protein in autoimmune diseases is a signal of damage that impairs endothelial cells through high-affinity membrane binding
IFI16, a nuclear pathogenic DNA sensor induced by several pro-inflammatory cytokines, is a
multifaceted protein with various functions. It is also a target for autoantibodies as specific …
multifaceted protein with various functions. It is also a target for autoantibodies as specific …
Comprehensive analysis identifies IFI16 as a novel signature associated with overall survival and immune infiltration of skin cutaneous melanoma
H Wang, X Xie, J Zhu, S Qi, J Xie - Cancer Cell International, 2021 - Springer
Background Skin cutaneous melanoma (SKCM) is the most common skin tumor with high
mortality. The unfavorable outcome of SKCM urges the discovery of prognostic biomarkers …
mortality. The unfavorable outcome of SKCM urges the discovery of prognostic biomarkers …
IFI16 mediates soluble Flt-1 and endoglin production by trophoblast cells
N Li, Y Fu, W Chen, GQ Hu, M Zhou, SX Yu… - Journal of …, 2015 - journals.lww.com
Objectives: Preeclampsia is a serious pregnancy-specific hypertensive syndrome that is
characterized by widespread maternal endothelial dysfunction. Previous studies have …
characterized by widespread maternal endothelial dysfunction. Previous studies have …
[PDF][PDF] 干扰素诱导蛋白家族成员IFI16 在肿瘤中作用的研究进展
邹云莲， 严新民 - 生命科学, 2016 - lifescience.sinh.ac.cn
IFI16 是干扰素诱导蛋白p200 家族中的人成员蛋白. IFI16 作为多功能效应蛋白参与细胞生长,
分化, 衰老, 凋亡及作为天然DNA 感受器参与细胞天然, 被动免疫反应过程. 近年发现IFI16 …
分化, 衰老, 凋亡及作为天然DNA 感受器参与细胞天然, 被动免疫反应过程. 近年发现IFI16 …
[PDF][PDF] DAMP-ening inflammation caused by Interferon Inducible Protein 16 (IFI16) in systemic autoimmunity
M Bawadekar - 2014 - iris.uniupo.it
2.1 AUTOIMMUNITY Autoimmunity is a diverse group of disorder that is characterized by the
production of antibodies that react with host tissues or immune effector cells that are …
production of antibodies that react with host tissues or immune effector cells that are …