Simple Summary Mutations of the NOTCH1 gene are a validated prognostic marker in
chronic lymphocytic leukemia and a potential predictive marker for anti-CD20-based …

Many functional consequences of mutations on tumor phenotypes in chronic lymphocytic
leukemia (CLL) are unknown. This may be in part due to a scarcity of information on the …

Retinal photoreceptor degeneration occurs frequently in several neurodegenerative retinal
diseases such as age-related macular degeneration, retinitis pigmentosa, or genetic retinal …

Simple Summary Despite continued efforts, the current status of knowledge in CLL
molecular pathobiology, diagnosis, prognosis and treatment remains elusive and imprecise …

Bruton tyrosine kinase (BTK) inhibitors are highly active drugs for the treatment of chronic
lymphocytic leukemia (CLL). To understand the response to BTK inhibitors on a molecular …

It is conceivable that spermatid apico-basal polarity and spermatid planar cell polarity (PCP)
are utmost important to support spermatogenesis. The orderly arrangement of developing …

Chronic lymphocytic leukemia (CLL) is an incurable malignant disease of B-lymphocytes
characterized by drastically heterogeneous clinical courses. Proteomics is an advanced …

Recent success in studying the proteome, as a source of biomarkers, has completely
changed our understanding of leukemia (blood cancer). The identification of differentially …

The systematic design and construction of customized protein microarrays are critical for the
further successful screening of biological samples in biomedical research projects. In …

Mantle cell lymphoma (MCL) is an aggressive B cell lymphoma that is largely
chemoresistant. Ibrutinib, a drug that inhibits Bruton's tyrosine kinase (BTK), has improved …