Surface functionalization of exosomes for target-specific delivery and in vivo imaging & tracking: Strategies and significance
Exosomes are natural nanovesicles excreted by many cells for intercellular communication
and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic …
and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic …
Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking
DE Murphy, OG de Jong, M Brouwer… - … & molecular medicine, 2019 - nature.com
Extracellular vesicles (EVs) are increasingly being recognized as mediators of intercellular
signaling via the delivery of effector molecules. Interestingly, certain types of EVs are also …
signaling via the delivery of effector molecules. Interestingly, certain types of EVs are also …
Native and bioengineered extracellular vesicles for cardiovascular therapeutics
RC de Abreu, H Fernandes… - Nature reviews …, 2020 - nature.com
Extracellular vesicles (EVs) are a heterogeneous group of natural particles that are relevant
to the treatment of cardiovascular diseases. These endogenous vesicles have certain …
to the treatment of cardiovascular diseases. These endogenous vesicles have certain …
Designer exosomes: a new platform for biotechnology therapeutics
Desirable features of exosomes have made them a suitable manipulative platform for
biomedical applications, including targeted drug delivery, gene therapy, cancer diagnosis …
biomedical applications, including targeted drug delivery, gene therapy, cancer diagnosis …
Exosomes as naturally occurring vehicles for delivery of biopharmaceuticals: insights from drug delivery to clinical perspectives
A Butreddy, N Kommineni, N Dudhipala - Nanomaterials, 2021 - mdpi.com
Exosomes as nanosized vesicles are emerging as drug delivery systems for therapeutics
owing to their natural origin, their ability to mediate intercellular communication, and their …
owing to their natural origin, their ability to mediate intercellular communication, and their …
Exosome: a significant nano-scale drug delivery carrier
H Peng, W Ji, R Zhao, J Yang, Z Lu, Y Li… - Journal of Materials …, 2020 - pubs.rsc.org
In recent years, due to the limitations of the nature of therapeutic agents, many synthetic
nano-delivery systems have emerged to enhance the efficacy of drugs. Extracellular vesicles …
nano-delivery systems have emerged to enhance the efficacy of drugs. Extracellular vesicles …
Exosomes Engineered to Express a Cardiomyocyte Binding Peptide Demonstrate Improved Cardiac Retention in Vivo
KI Mentkowski, JK Lang - Scientific reports, 2019 - nature.com
Injury to the heart results in cardiomyocyte cell death and can lead to pathological
remodeling of remaining cells, contributing to heart failure. Despite the therapeutic potential …
remodeling of remaining cells, contributing to heart failure. Despite the therapeutic potential …
Exosomes as drug delivery systems: A brief overview and progress update
Exosomes are intracellular membrane-based vesicles with diverse compositions that are
involved in biological and pathological processes. Since the discovery of exosomes, they …
involved in biological and pathological processes. Since the discovery of exosomes, they …
Bionanoparticles in cancer imaging, diagnosis, and treatment
Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …
Engineered extracellular vesicles for bone therapy
Extracellular vesicles, which are secreted by living cells and play a critical role in cellular
communication, have emerged as a promising cell-free strategy in the treatment of many …
communication, have emerged as a promising cell-free strategy in the treatment of many …