Natural bioactive compounds-doxorubicin combinations targeting topoisomerase II-alpha: Anticancer efficacy and safety
A Elfadadny, RF Ragab, R Hamada… - Toxicology and Applied …, 2023 - Elsevier
Cancer is one of the leading causes of death worldwide, so pursuing effective and safe
therapeutics for cancer is a key research objective nowadays. Doxorubicin (DOX) is one of …
therapeutics for cancer is a key research objective nowadays. Doxorubicin (DOX) is one of …
Design and development of novel nutraceuticals: Current trends and methodologies
Over the past few years, nutraceuticals have gained substantial attention due to the health-
promoting and disease-preventing functions behind their nutritional value. The global …
promoting and disease-preventing functions behind their nutritional value. The global …
Formulation, Optimization, and Evaluation of Moringa oleifera Leaf Polyphenol-Loaded Phytosome Delivery System against Breast Cancer Cell Lines
Moringa oleifera leaf polyphenols (Mopp) were encapsulated with phytosomes to enhance
their efficacy on 4T1 cancer cell lines. The Mopp were extracted via microwave-assisted …
their efficacy on 4T1 cancer cell lines. The Mopp were extracted via microwave-assisted …
Rutin attenuates D-galactose-induced oxidative stress in rats' brain and liver: molecular docking and experimental approaches
SM Saafan, SA Mohamed, AE Noreldin… - Food & Function, 2023 - pubs.rsc.org
Oxidative stress results from the imbalance between reactive oxygen species (ROS)
production and antioxidant defence and is primarily involved in aging. The current study …
production and antioxidant defence and is primarily involved in aging. The current study …
Carbon nanofibers versus silver nanoparticles: Time-dependent cytotoxicity, proliferation, and gene expression
Carbon nanofibers (CNFs) are one-dimensional nanomaterials with excellent physical and
broad-spectrum antimicrobial properties characterized by a low risk of antimicrobial …
broad-spectrum antimicrobial properties characterized by a low risk of antimicrobial …
The emerging potential of parthenolide nanoformulations in tumor therapy
T An, H Yin, Y Lu, F Liu - Drug Design, Development and Therapy, 2023 - Taylor & Francis
Plant-derived sesquiterpene lactones are promising natural sources for the discovery of anti-
cancer drugs. As an extensively studied sesquiterpene lactone, the tumor suppression effect …
cancer drugs. As an extensively studied sesquiterpene lactone, the tumor suppression effect …
[HTML][HTML] SPME and solvent-based GC–MS metabolite profiling of Egyptian marketed Saussurea costus (Falc.) Lipsch. concerning its anticancer activity
Abstract Background Saussurea costus Falc with synonymous Aucklandia costus, S. lappa,
and A. lappa, is an ancient perennial plant native to Himalayan region. Purpose S. costus …
and A. lappa, is an ancient perennial plant native to Himalayan region. Purpose S. costus …
Green synthesis of Brassica carinata microgreen silver nanoparticles, characterization, safety assessment, and antimicrobial activities
Nanotechnology has been a central focus of scientific investigation over the past decades
owing to its versatile applications. The synthesis of silver nanoparticles (AgNPs) through …
owing to its versatile applications. The synthesis of silver nanoparticles (AgNPs) through …
Phytosesquiterpene lactones deregulate mitochondrial activity and phenotypes associated with triple-negative breast cancer metastasis
Background Triple-negative breast cancer (TNBC) recurrence and metastasis are the major
causes of failure in TNBC therapy. The difficulties in treating TNBCs may be because of …
causes of failure in TNBC therapy. The difficulties in treating TNBCs may be because of …
Inhibiting AGS Cancer Cell Proliferation through the Combined Application of Aucklandiae Radix and Hyperthermia: Investigating the Roles of Heat Shock Proteins …
Cancer is a major global health concern. To address this, the combination of traditional
medicine and newly appreciated therapeutic modalities has been gaining considerable …
medicine and newly appreciated therapeutic modalities has been gaining considerable …