Vitamin D insufficiency or deficiency (VDD) is a very prevalent condition in the general
population. Vitamin D is necessary for optimal bone mineralization, but apart from the bone …

Twenty of the last one hundred years of vitamin D research have involved investigations of
the brain as a target organ for this hormone. Our group was one of the first to investigate …

It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

Many epidemiological studies have highlighted the link between vitamin D deficiency and
schizophrenia. In particular, two prominent studies report an association between neonatal …

The aim of this study is to determine and critically evaluate the plausible relationships of
vitamin D with extra-skeletal tissues in humans. Severe vitamin D deficiency results in rickets …

Vitamin D system comprises hormone precursors, active metabolites, carriers, enzymes, and
receptors involved in genomic and non-genomic effects. In addition to classical bone-related …

Since its discovery during the epidemic of rickets in the early 1920s, the physiological effects
of vitamin D on calcium/phosphorus homeostasis have been thoroughly studied. Along with …

Vitamin D is a hormone with both genomic and non-genomic actions. It exerts its activity by
binding vitamin D receptor (VDR), which belongs to the superfamily of nuclear receptors and …

Background Hypovitaminosis D, a condition that is highly prevalent in older adults aged 65
years and above, is associated with brain changes and dementia. Given the rapidly …

It has been 20 years since we first proposed vitamin D as a “possible” neurosteroid.(1) Our
work over the last two decades, particularly results from our cellular and animal models, has …