Hashimotos' thyroiditis: Epidemiology, pathogenesis, clinic and therapy

F Ragusa, P Fallahi, G Elia, D Gonnella… - Best Practice & …, 2019 - Elsevier
Hashimoto's thyroiditis (HT), the most frequent autoimmune thyroid disorders (AITDs), is the
leading cause of hypothyroidism in the iodine-sufficient areas of the world. About 20–30% of …

Graves' disease: Epidemiology, genetic and environmental risk factors and viruses

A Antonelli, SM Ferrari, F Ragusa, G Elia… - Best practice & research …, 2020 - Elsevier
Graves' disease (GD) is the most common cause of hyperthyroidism in developed Countries.
It is more common between 30 and 60 years; 5–10 times more frequent in women. The …

Th1 chemokines in autoimmune endocrine disorders

P Fallahi, SM Ferrari, F Ragusa, I Ruffilli… - The Journal of …, 2020 - academic.oup.com
Context The CXC chemokine receptor CXCR3 and its chemokines CXCL10, CXCL9, and
CXCL11 are implicated in the pathogenesis of autoimmune diseases. Here, we review these …

Endocrine disruptors and thyroid autoimmunity

S Benvenga, G Elia, F Ragusa, SR Paparo… - Best Practice & …, 2020 - Elsevier
Many papers evaluated the effect of the environmental, or occupational endocrine disruptors
(ED), on the thyroid gland, that can lead to thyroid autoimmunity. A higher prevalence of …

[HTML][HTML] Chemokines in thyroid autoimmunity

SM Ferrari, SR Paparo, F Ragusa, G Elia… - Best Practice & …, 2023 - Elsevier
The chemokine receptor CXCR3 and its chemokines CXCL9, CXCL10, and CXCL11 are
involved in the pathogenesis of autoimmune diseases. Th1 lymphocytes are recruited by …

Precision medicine in autoimmune thyroiditis and hypothyroidism

SM Ferrari, F Ragusa, G Elia, SR Paparo… - Frontiers in …, 2021 - frontiersin.org
Autoimmune thyroid diseases (AITD) are T-cell-mediated organ specific autoimmune
disorders, deriving from an altered response of the immune system that leads to the immune …

Cytokines as targets of novel therapies for Graves' ophthalmopathy

P Fallahi, SM Ferrari, G Elia, F Ragusa… - Frontiers in …, 2021 - frontiersin.org
Graves' disease (GD) is an organ-specific autoimmune disorder of the thyroid, which is
characterized by circulating TSH-receptor (TSH-R) stimulating antibodies (TSAb), leading to …

Virus-driven autoimmunity and lymphoproliferation: the example of HCV infection

AL Zignego, L Gragnani, A Piluso… - Expert review of …, 2015 - Taylor & Francis
HCV chronic infection is characterized by possible development of both hepatic and
extrahepatic manifestations. The infection by this both hepatotropic and lymphotropic virus is …

[HTML][HTML] Chemokines in hyperthyroidism

SM Ferrari, I Ruffilli, G Elia, F Ragusa… - Journal of clinical & …, 2019 - Elsevier
The term “hyperthyroidism” indicates a condition due to an exaggerate production of thyroid
hormone; the most frequent cause is Graves' disease (GD). We review cytokines and …

Thyroid autoimmunity and SARS-CoV-2 infection

P Fallahi, G Elia, F Ragusa, SR Paparo… - Journal of Clinical …, 2023 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological culprit
of COronaVIrus Disease 19 (COVID-19), can enter the cells via the angiotensin-converting …