Diversity in bacterial lysis systems: bacteriophages show the way

MJ Catalao, F Gil, J Moniz-Pereira… - FEMS microbiology …, 2013 - academic.oup.com
Bacteriophages have developed multiple host cell lysis strategies to promote release of
descendant virions from infected bacteria. This review is focused on the lysis mechanisms …

[HTML][HTML] On the nature of mycobacteriophage diversity and host preference

D Jacobs-Sera, LJ Marinelli, C Bowman… - Virology, 2012 - Elsevier
The complete genome sequences of over 220 mycobacteriophages reveal them to be highly
diverse, with numerous types sharing little or no nucleotide sequence identity with each …

A broadly implementable research course in phage discovery and genomics for first-year undergraduate students

TC Jordan, SH Burnett, S Carson, SM Caruso, K Clase… - MBio, 2014 - Am Soc Microbiol
Engaging large numbers of undergraduates in authentic scientific discovery is desirable but
difficult to achieve. We have developed a general model in which faculty and teaching …

Amplifying genetic logic gates

J Bonnet, P Yin, ME Ortiz, P Subsoontorn, D Endy - Science, 2013 - science.org
Organisms must process information encoded via developmental and environmental signals
to survive and reproduce. Researchers have also engineered synthetic genetic logic to …

[图书][B] Molecular genetics of mycobacteria

GF Hatfull, WR Jacobs Jr - 2020 - books.google.com
A comprehensive collection of perspectives by experts in mycobacterial molecular biology
Mycobacterium tuberculosis causes one in four avoidable deaths in the developing world …

Molecular genetics of mycobacteriophages

GF Hatfull - Molecular genetics of mycobacteria, 2014 - Wiley Online Library
Mycobacteriophages are viruses that infect mycobacterial hosts including Mycobacterium
smegmatis and Mycobacterium tuberculosis. The first mycobacteriophages were isolated in …

Mycobacteriophage endolysins: diverse and modular enzymes with multiple catalytic activities

KM Payne, GF Hatfull - PLoS One, 2012 - journals.plos.org
The mycobacterial cell wall presents significant challenges to mycobacteriophages–viruses
that infect mycobacterial hosts–because of its unusual structure containing a mycolic acid …

Mycobacteriophages: windows into tuberculosis

GF Hatfull - PLoS pathogens, 2014 - journals.plos.org
Mycobacteriophages are viruses that infect mycobacterial hosts, such as Mycobacterium
tuberculosis and Mycobacterium smegmatis [1]. Because the discovery and genomic …

Integration-dependent bacteriophage immunity provides insights into the evolution of genetic switches

GW Broussard, LM Oldfield, VM Villanueva, BL Lunt… - Molecular cell, 2013 - cell.com
Genetic switches are critical components of developmental circuits. Because temperate
bacteriophages are vastly abundant and greatly diverse, they are rich resources for …

Propionibacterium acnes bacteriophages display limited genetic diversity and broad killing activity against bacterial skin isolates

LJ Marinelli, S Fitz-Gibbon, C Hayes, C Bowman… - MBio, 2012 - Am Soc Microbiol
Investigation of the human microbiome has revealed diverse and complex microbial
communities at distinct anatomic sites. The microbiome of the human sebaceous follicle …