Bacteriocins produced by lactic acid bacteria (LAB-bacteriocins) may serve as alternatives
for aging antibiotics. LAB-bacteriocins can be used alone, or in some cases as potentiating …

Bacteriocins are bacterially produced antimicrobial peptides with narrow or broad host
ranges. Many bacteriocins are produced by food-grade lactic acid bacteria, a phenomenon …

Lipid II is a membrane-anchored cell-wall precursor that is essential for bacterial cell-wall
biosynthesis. The effectiveness of targeting Lipid II as an antibacterial strategy is highlighted …

Lantibiotics are peptide-derived antimicrobial agents that are ribosomally synthesized and
posttranslationally modified to their biologically active forms. The name lantibiotics was …

The current need for antibiotics with novel target molecules has coincided with advances in
technical approaches for the structural and functional analysis of the lantibiotics, which are …

The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

The emerging antibiotics-resistance problem has underlined the urgent need for novel
antimicrobial agents. Lantibiotics (lanthionine-containing antibiotics) are promising …

Natural products remain a critical source of medicines and drug leads. One of the most
rapidly growing superclasses of natural products is RiPPs: ribosomally synthesized and …

Enterococcus faecalis is a Gram-positive commensal member of the gut microbiota of a wide
range of organisms. With the advent of antibiotic therapy, it has emerged as a multidrug …

The peptidoglycan layers surrounding bacterial membranes are essential for bacterial cell
survival and provide an important target for antibiotics. Many antibiotics have mechanisms of …