Organic semiconducting agents for deep‐tissue molecular imaging: second near‐infrared fluorescence, self‐luminescence, and photoacoustics

Q Miao, K Pu - Advanced materials, 2018 - Wiley Online Library
Optical imaging has played a pivotal role in biology and medicine, but it faces challenges of
relatively low tissue penetration and poor signal‐to‐background ratio due to light scattering …

A practical guide to photoacoustic tomography in the life sciences

LV Wang, J Yao - Nature methods, 2016 - nature.com
The life sciences can benefit greatly from imaging technologies that connect microscopic
discoveries with macroscopic observations. One technology uniquely positioned to provide …

Contrast agents for molecular photoacoustic imaging

J Weber, PC Beard, SE Bohndiek - Nature methods, 2016 - nature.com
Photoacoustic imaging (PAI) is an emerging tool that bridges the traditional depth limits of
ballistic optical imaging and the resolution limits of diffuse optical imaging. Using the …

[HTML][HTML] Photoacoustic tomography: principles and advances

J Xia, J Yao, LV Wang - Electromagnetic waves (Cambridge, Mass …, 2014 - ncbi.nlm.nih.gov
Photoacoustic tomography (PAT) is an emerging imaging modality that shows great
potential for preclinical research and clinical practice. As a hybrid technique, PAT is based …

Advanced optoacoustic methods for multiscale imaging of in vivo dynamics

XL Deán-Ben, S Gottschalk, B Mc Larney… - Chemical Society …, 2017 - pubs.rsc.org
Visualization of dynamic functional and molecular events in an unperturbed in vivo
environment is essential for understanding the complex biology of living organisms and of …

Deep in vivo photoacoustic imaging of mammalian tissues using a tyrosinase-based genetic reporter

AP Jathoul, J Laufer, O Ogunlade, B Treeby, B Cox… - Nature …, 2015 - nature.com
Photoacoustic imaging allows absorption-based high-resolution spectroscopic in vivo
imaging at a depth beyond that of optical microscopy. Until recently, photoacoustic imaging …

Emerging designs of activatable photoacoustic probes for molecular imaging

Q Miao, K Pu - Bioconjugate chemistry, 2016 - ACS Publications
Photoacoustic (PA) imaging as a new hybrid imaging modality holds great promise for real-
time in vivo monitoring of biological processes with deep tissue penetration and high spatial …

Photoacoustic brain imaging: from microscopic to macroscopic scales

J Yao, LV Wang - Neurophotonics, 2014 - spiedigitallibrary.org
Human brain mapping has become one of the most exciting contemporary research areas,
with major breakthroughs expected in the coming decades. Modern brain imaging …

[HTML][HTML] New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles

EY Park, D Oh, S Park, W Kim, C Kim - APL bioengineering, 2021 - pubs.aip.org
The phthalocyanine (Pc) and naphthalocyanine (Nc) nanoagents have drawn much
attention as contrast agents for photoacoustic (PA) imaging due to their large extinction …

Photoacoustic imaging using genetically encoded reporters: a review

J Brunker, J Yao, J Laufer… - Journal of biomedical …, 2017 - spiedigitallibrary.org
Genetically encoded contrast in photoacoustic imaging (PAI) is complementary to the
intrinsic contrast provided by endogenous absorbing chromophores such as hemoglobin …