The metabolic signals that regulate sleep and the metabolic functions that occur during
sleep are active areas of research. Prior studies have focused on sugars and nucleotides …

Providing metabolic support to neurons is now recognized as a major function of glial cells
that is conserved from invertebrates to vertebrates. However, research in this field has …

Sleep is broadly conserved across the animal kingdom but can vary widely between
species. It is currently unclear which selective pressures and regulatory mechanisms …

Lipid droplets (LDs) are dynamic lipid storage organelles. They are tightly linked to
metabolism and can exert protective functions, making them important players in health and …

Intellectual disability is defined as limitations in cognitive and adaptive behavior that often
arise during development. Disordered sleep is common in intellectual disability and, given …

The neural control of sleep requires that sleep need is sensed during waking and
discharged during sleep. To obtain a comprehensive, unbiased view of molecular changes …

Biological rhythms play a crucial role in temporally regulating behavioral, physiological, and
cellular processes within our bodies. One prominent example is the circadian rhythm, which …

Dysregulation of sleep has widespread health consequences and represents an enormous
health burden. Short-sleeping individuals are predisposed to the effects of …

Circadian clock disruption and lack of sleep impair health of cells and organs, but
mechanisms remain elusive. Here, we used multi-omics, molecular and functional assays in …

Lipid changes in the brain have been implicated in many neurodegenerative diseases
including Alzheimer's Disease (AD), Parkinson's disease and Amyotrophic Lateral Sclerosis …