Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease characterized by
autoimmune destruction of small to medium size intrahepatic bile ducts. The etiology of PBC …

One of the major disappointments in human autoimmunity has been the relative failure on
genome-wide association studies to provide “smoking genetic guns” that would explain the …

Abstract Inhibition of microRNA-21 (miR-21) prevents necroptosis in the mouse pancreas.
Necroptosis contributes to hepatic necro-inflammation in the common bile duct ligation …

Hepatocellular carcinoma (HCC) is one of the leading global causes of cancer mortality.
MicroRNAs (miRNAs) are small interfering RNAs that alleviate the levels of protein …

In response to oxidative stress, nuclear factor (erythroid-derived 2)-like2 (Nrf2) induces
expression of cytoprotective genes. The Nrf2 pathway is controlled by microRNAs and Kelch …

Primary biliary cirrhosis (PBC) is a chronic cholestatic immune liver disease characterized
by persistent cholestasis, interlobular bile duct damage, portal inflammation, liver fibrosis …

Cholangiocarcinoma (CCA) are a heterogeneous group of tumors in terms of aetiology,
natural history, morphological subtypes, molecular alterations and management, but all …

Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease associated with
autoimmune-related destruction of small to medium size intrahepatic bile ducts. The …

Primary Biliary Cholangitis (PBC) is a rare autoimmune disease of the liver, affecting mostly
females. There is evidence that epigenetic changes have a pathogenic role in PBC …

Primary biliary cholangitis (PBC) is an autoimmune liver disease characterised by the
immune-mediated destruction of small and medium intrahepatic bile ducts, with variable …