Bone is the second most commonly transplanted tissue worldwide, with over four million
operations using bone grafts or bone substitute materials annually to treat bone defects …

Regenerative engineering converges tissue engineering, advanced materials science, stem
cell science, and developmental biology to regenerate complex tissues such as whole limbs …

The worldwide incidence of bone disorders and conditions has trended steeply upward and
is expected to double by 2020, especially in populations where aging is coupled with …

Tendon injuries are a global health problem that affects millions of people annually. The
properties of tendons make their natural rehabilitation a very complex and long-lasting …

As dense connective tissues connecting bone to muscle and bone to bone, respectively,
tendon and ligament (T/L) arise from the somitic mesoderm, originating in a recently …

Inkjet bioprinting is one of the most promising additive manufacturing approaches for tissue
fabrication with the advantages of high speed, high resolution, and low cost. The limitation of …

The molecular and physical information coded within the extracellular milieu is informing the
development of a new generation of biomaterials for tissue engineering. Several powerful …

Bioprinting based on thermal inkjet printing is a promising but unexplored approach in bone
tissue engineering. Appropriate cell types and suitable biomaterial scaffolds are two critical …

Integration between tendon/ligament and bone occurs through a specialized tissue interface
called enthesis. The complex and heterogeneous structure of the enthesis is essential to …

Tendon/ligament-to-bone healing poses a formidable clinical challenge due to the complex
structure, composition, cell population and mechanics of the interface. With rapid advances …