Shine & Lal index as a predictor for early detection of β-thalassemia carriers in a limited resource area in Bandung, Indonesia
Abstracts Background Thalassemia is the most common inherited disease in the world,
involving α-or β-globin in red blood cells. Thalassemia cases rank fifth in the list of national …
involving α-or β-globin in red blood cells. Thalassemia cases rank fifth in the list of national …
δ-Hemoglobinopathies in Thailand: screening, molecular basis, genotype-phenotype interaction, and implication for prevention and control of thalassemia
K Singha, G Fucharoen, S Fucharoen - Annals of Hematology, 2021 - Springer
The δ-globin gene defects are clinically silent but interaction with β-thalassemia can lead to
a misdiagnosis of β-thalassemia carrier. We report an extensive molecular characterization …
a misdiagnosis of β-thalassemia carrier. We report an extensive molecular characterization …
Molecular epidemiology, pathogenicity, and structural analysis of haemoglobin variants in the Yunnan province population of Southwestern China
J Zhang, P Li, Y Yang, Y Yan, X Zeng, D Li, H Chen… - Scientific Reports, 2019 - nature.com
Abnormal haemoglobin (Hb) variants result in the most commonly inherited disorders in
humans worldwide. In this study, we investigated the molecular epidemiology characteristics …
humans worldwide. In this study, we investigated the molecular epidemiology characteristics …
Hemoglobin variants in Northern Thailand: prevalence, heterogeneity and molecular characteristics
S Panyasai, G Fucharoen… - Genetic Testing and …, 2016 - liebertpub.com
Background: There are limited data on hemoglobin (Hb) variants among peoples of northern
Thailand. Hence, we determined the prevalence of Hb variants among a large cohort from …
Thailand. Hence, we determined the prevalence of Hb variants among a large cohort from …
Phenotypic expression of known and novel hemoglobin A2-Variants, hemoglobin A2-Mae phrik [Delta 52 (D3) asp> gly, HBD: c. 158A> G], associated with …
A Phasit, S Panyasai, M Mayoon, N Jettawan… - Genes, 2022 - mdpi.com
The interactions of δ-globin variants with α-and β-thalassemia or other hemoglobinopathies
cause complex thalassemic syndromes and potential diagnostic problems. Understanding …
cause complex thalassemic syndromes and potential diagnostic problems. Understanding …
Diagnosis of common hemoglobinopathies among South East Asian population using capillary isoelectric focusing system
H Srivorakun, G Fucharoen… - … journal of laboratory …, 2017 - Wiley Online Library
Introduction We have evaluated an automated capillary isoelectric focusing (cIEF)‐based Hb
analyzer in diagnosis of hemoglobinopathies commonly found among South East Asian …
analyzer in diagnosis of hemoglobinopathies commonly found among South East Asian …
Highly sensitive detection of the PIK3CA H1047R mutation in colorectal cancer using a novel PCR-RFLP method
WM Li, TT Hu, LL Zhou, YM Feng, YY Wang, J Fang - BMC cancer, 2016 - Springer
Abstract Background The PIK3CA H1047R mutation is considered to be a potential
predictive biomarker for EGFR-targeted therapies. In this study, we developed a novel PCR …
predictive biomarker for EGFR-targeted therapies. In this study, we developed a novel PCR …
[HTML][HTML] Thalassemia and erythroid transcription factor KLF1 mutations associated with borderline hemoglobin A2 in the Thai population
H Srivorakun, W Thawinan, G Fucharoen… - Archives of Medical …, 2022 - ncbi.nlm.nih.gov
Results Among 202 subjects, DNA analysis identified carriers of α+-thalassemia (n= 48;
23.8%), β-thalassemia (n= 22; 10.9%) and KLF1 mutations (n= 48; 23.8%). No molecular …
23.8%), β-thalassemia (n= 22; 10.9%) and KLF1 mutations (n= 48; 23.8%). No molecular …
Hematological and Molecular Characterization of a Novel Hb A2 Variant with Homozygous α-Thalassemia-2 in a Southern Thai Individual
M Nuinoon, N Jeenduang, A Kesornsit, D Horpet… - …, 2017 - Taylor & Francis
We report here the hematological and molecular features of a novel δ-globin chain variant
found in a Southern Thai woman. Her complete blood count was as follows: red blood cell …
found in a Southern Thai woman. Her complete blood count was as follows: red blood cell …
Prospective screening for δ-hemoglobinopathies associated with decreased hemoglobin A2 levels or hemoglobin A2 variants: A single center experience
C Hanart, K Singha, Y Changtrakul, S Fucharoen… - Clinica Chimica …, 2023 - Elsevier
Background δ-hemoglobinopathies may lead to misdiagnosis of several thalassemia
syndromes especially β-thalassaemia carrier, it is important to evaluate the δ-globin gene …
syndromes especially β-thalassaemia carrier, it is important to evaluate the δ-globin gene …