Stilbenes are polyphenolic allelochemicals synthesized by plants, especially grapes,
peanuts, rhubarb, berries, etc., to defend themselves under stressful conditions. They are …

Neuroinflammation is a pathological feature of quite a number of Central Nervous System
diseases such as Alzheimer and Parkinson's disease among others. The hallmark of brain …

Atherosclerosis is a chronic inflammatory disease of the vascular arterial walls. A number of
studies have revealed the biological and genetic bases of atherosclerosis, and over 100 …

Background/Aims Septic cardiomyopathy is a severe condition that remains a challenge for
clinical management. This study investigated whether the natural polyphenolic compound …

Significance: Many physiological effects of natural antioxidants, their extracts or their major
active components, have been reported in recent decades. Most of these compounds are …

Scope Grapevine‐shoot extract Vineatrol30 contains abundant resveratrol monomers and
oligomers with health‐promoting potential. However, the oral bioavailability of these …

Nuclear factor-erythroid 2-related factor 2 (Nrf2), a transcription factor, controls the
expression of more than 1000 genes that can be clustered into different categories with …

The redox-sensitive signaling system Keap1/Nrf2/ARE plays a key role in maintenance of
cellular homeostasis under stress, inflammatory, carcinogenic, and proapoptotic conditions …

Hypoxia is the failure of oxygenation at the tissue level, where the reduced oxygen delivered
is not enough to satisfy tissue demands. Metabolic depression is the physiological …

Oxidative stress is considered to play an important role in the pathogenesis of diabetes-
induced cardiovascular disease (CVD), which is invariably associated with abnormal blood …