Whole‐body endothermy: ancient, homologous and widespread among the ancestors of mammals, birds and crocodylians

G Grigg, J Nowack, JEPW Bicudo, NC Bal… - Biological …, 2022 - Wiley Online Library
The whole‐body (tachymetabolic) endothermy seen in modern birds and mammals is long
held to have evolved independently in each group, a reasonable assumption when it was …

[PDF][PDF] Skeletal muscle thermogenesis and its role in whole body energy metabolism

M Periasamy, JL Herrera… - Diabetes & metabolism …, 2017 - synapse.koreamed.org
Obesity and diabetes has become a major epidemic across the globe. Controlling obesity
has been a challenge since this would require either increased physical activity or reduced …

UCP1-independent thermogenesis

A Roesler, L Kazak - Biochemical Journal, 2020 - portlandpress.com
Obesity results from energy imbalance, when energy intake exceeds energy expenditure.
Brown adipose tissue (BAT) drives non-shivering thermogenesis which represents a …

[HTML][HTML] Browning of white adipose tissue: lessons from experimental models

TCL Bargut, V Souza-Mello, MB Aguila… - … molecular biology and …, 2017 - degruyter.com
Beige or brite (brown-in-white) adipocytes are present in white adipose tissue (WAT) and
have a white fat-like phenotype that when stimulated acquires a brown fat-like phenotype …

Muscle non-shivering thermogenesis and its role in the evolution of endothermy

J Nowack, S Giroud, W Arnold, T Ruf - Frontiers in physiology, 2017 - frontiersin.org
The development of sustained, long-term endothermy was one of the major transitions in the
evolution of vertebrates. Thermogenesis in endotherms does not only occur via shivering or …

ATP-consuming futile cycles as energy dissipating mechanisms to counteract obesity

AJ Brownstein, M Veliova, R Acin-Perez… - Reviews in Endocrine …, 2022 - Springer
Obesity results from an imbalance in energy homeostasis, whereby excessive energy intake
exceeds caloric expenditure. Energy can be dissipated out of an organism by producing …

Seasonal cold induces divergent structural/biochemical adaptations in different skeletal muscles of Columba livia: evidence for nonshivering thermogenesis in adult …

P Pani, G Swalsingh, S Pani, U Senapati… - Biochemical …, 2023 - portlandpress.com
Birds are endothermic homeotherms even though they lack the well-studied heat producing
brown adipose tissue (BAT), found in several clades of eutherian mammals. Earlier studies …

Hypothermia in newly born piglets: Mechanisms of thermoregulation and pathophysiology of death

D Villanueva-García, D Mota-Rojas… - Journal of Animal …, 2020 - jabbnet.com
Mortality in piglets during the perinatal period, especially the first days after birth, is
frequently caused by non-infectious conditions, such as hypoglucemia or low birth weight …

Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice

NC Bal, S Singh, FCG Reis, SK Maurya, S Pani… - Journal of Biological …, 2017 - ASBMB
Thermogenesis is an important homeostatic mechanism essential for survival and normal
physiological functions in mammals. Both brown adipose tissue (BAT)(ie uncoupling protein …

Four‐week cold acclimation in adult humans shifts uncoupling thermogenesis from skeletal muscles to brown adipose tissue

DP Blondin, A Daoud, T Taylor… - The Journal of …, 2017 - Wiley Online Library
Key points Muscle‐derived thermogenesis during acute cold exposure in humans consists
of a combination of cold‐induced increases in skeletal muscle proton leak and shivering …