Aβ-oligomers: A potential therapeutic target for Alzheimer's disease
The cascade of amyloid formation relates to multiple complex events at the molecular level.
Previous research has established amyloid plaque deposition as the leading cause of …
Previous research has established amyloid plaque deposition as the leading cause of …
[HTML][HTML] Microglial activation and priming in Alzheimer's disease: state of the art and future perspectives
Alzheimer's Disease (AD) is the most common cause of dementia, having a remarkable
social and healthcare burden worldwide. Amyloid β (Aβ) and protein Tau aggregates are …
social and healthcare burden worldwide. Amyloid β (Aβ) and protein Tau aggregates are …
[HTML][HTML] Therapeutic strategies aimed at improving neuroplasticity in Alzheimer disease
MF Colavitta, FJ Barrantes - Pharmaceutics, 2023 - mdpi.com
Alzheimer disease (AD) is the most prevalent form of dementia among elderly people.
Owing to its varied and multicausal etiopathology, intervention strategies have been highly …
Owing to its varied and multicausal etiopathology, intervention strategies have been highly …
[HTML][HTML] CX3CL1 pathway as a molecular target for treatment strategies in Alzheimer's disease
G Bivona, M Iemmolo, G Ghersi - International Journal of Molecular …, 2023 - mdpi.com
Alzheimer's disease (AD) is a scourge for patients, caregivers and healthcare professionals
due to the progressive character of the disease and the lack of effective treatments. AD is …
due to the progressive character of the disease and the lack of effective treatments. AD is …
[HTML][HTML] Unveiling the molecular Footprint: Proteome-based biomarkers for Alzheimer's disease
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by
progressive cognitive decline and memory loss. Early and accurate diagnosis of AD is …
progressive cognitive decline and memory loss. Early and accurate diagnosis of AD is …
[HTML][HTML] Realization of amyloid-like aggregation as a common cause for pathogenesis in diseases
S Naskar, N Gour - Life, 2023 - mdpi.com
Amyloids were conventionally referred to as extracellular and intracellular accumulation of
Aβ42 peptide, which causes the formation of plaques and neurofibrillary tangles inside the …
Aβ42 peptide, which causes the formation of plaques and neurofibrillary tangles inside the …
Neuroprotective and anti‐inflammatory effects of curcumin in Alzheimer's disease: Targeting neuroinflammation strategies
E Azzini, SI Peña‐Corona… - Phytotherapy …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the
accumulation of amyloid‐beta plaques and neurofibrillary tangles, leading to neuronal loss …
accumulation of amyloid‐beta plaques and neurofibrillary tangles, leading to neuronal loss …
[HTML][HTML] Anxiety adds the risk of cognitive progression and is associated with axon/synapse degeneration among cognitively unimpaired older adults
L Sun, W Li, Q Qiu, Y Hu, Z Yang, S Xiao - EBioMedicine, 2023 - thelancet.com
Background Mental symptoms have been shown to be associated with dementia. As the
most common neuropsychiatric disorder, it is unclear whether and why anxiety increases the …
most common neuropsychiatric disorder, it is unclear whether and why anxiety increases the …
An axis-referenced morphometric model reshaping the hippocampus following its longitudinal organization
The anterior-posterior gradient of the human hippocampus on coronal slices is commonly
referred to as the long axis, which exhibits morphological heterogeneity related to aging and …
referred to as the long axis, which exhibits morphological heterogeneity related to aging and …