MicroRNA-122 in human cancers: from mechanistic to clinical perspectives

M Faramin Lashkarian, N Hashemipour… - Cancer Cell …, 2023 - Springer
MicroRNAs (miRNAs) are endogenous short non-coding RNAs that can regulate the
expression of target genes post-transcriptionally and interact with mRNA-coding genes …

Molecular mediators of RNA loading into extracellular vesicles

C Corrado, MM Barreca, C Zichittella, R Alessandro… - Cells, 2021 - mdpi.com
In the last decade, an increasing number of studies have demonstrated that non-coding
RNA (ncRNAs) cooperate in the gene regulatory networks with other biomolecules …

A novel electrochemical biosensor based on signal amplification of Au HFGNs/PnBA-MXene nanocomposite for the detection of miRNA-122 as a biomarker of breast …

S Ranjbari, M Rezayi, R Arefinia, SH Aghaee-Bakhtiari… - Talanta, 2023 - Elsevier
Cancer is one of the leading causes of death worldwide and a crisis for global health. Breast
cancer is the second most common cancer globally. In the perusal, a novel electrochemical …

Circulating cell-free nucleic acids as epigenetic biomarkers in precision medicine

B Rahat, T Ali, D Sapehia, A Mahajan, J Kaur - Frontiers in genetics, 2020 - frontiersin.org
The circulating cell-free nucleic acids (ccfNAs) are a mixture of single-or double-stranded
nucleic acids, released into the blood plasma/serum by different tissues via apoptosis …

Emergence of circulating MicroRNAs in breast cancer as diagnostic and therapeutic efficacy biomarkers

V Aggarwal, K Priyanka, HS Tuli - Molecular diagnosis & therapy, 2020 - Springer
Breast cancer is the second most common cause of deaths reported in women worldwide,
and therefore there is a need to identify breast cancer patients at an early stage as timely …

Potential utility of miRNAs for liquid biopsy in breast cancer

X Liu, D Papukashvili, Z Wang, Y Liu, X Chen… - Frontiers in …, 2022 - frontiersin.org
Breast cancer (BC) remains the most prevalent malignancy due to its incidence rate,
recurrence, and metastasis in women. Conventional strategies of cancer detection …

The role and mechanism of action of microRNA-122 in cancer: Focusing on the liver

ME Al-Gazally, R Khan, M Imran… - International …, 2023 - Elsevier
Abstract microRNA-122 (miR-122) is a highly conserved microRNA that is predominantly
expressed in the liver and plays a critical role in the regulation of liver metabolism. Recent …

microRNAs signature in relapse metastasis and de novo metastasis of breast cancer. A systematic review

C González-Martínez, C Garrido-Navas… - Critical reviews in …, 2023 - Elsevier
Abstract miRNAs have been widely identified as important players in cancer development
and progression. Metastasis in breast cancer can occur as relapse of a treated primary …

miR‐122‐5p promotes aggression and epithelial‐mesenchymal transition in triple‐negative breast cancer by suppressing charged multivesicular body protein 3 …

Z Wang, X Wang - Journal of cellular physiology, 2020 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is highly metastatic and frequently has a poor
prognosis. The lack of comprehension of TNBC and gene therapy targets has led to limitedly …

Predictive and prognostic value of non-coding RNA in breast cancer

N Sobhani, R Chahwan, R Roudi, R Morris, S Volinia… - Cancers, 2022 - mdpi.com
Simple Summary In our journey to fight cancer, biomarkers for prediction and efficacy of
therapies could help medical practitioners to give patients the best available treatments in a …