Targeting the microenvironment of vulnerable atherosclerotic plaques: an emerging diagnosis and therapy strategy for atherosclerosis

S Zhang, Y Liu, Y Cao, S Zhang, J Sun… - Advanced …, 2022 - Wiley Online Library
Atherosclerosis is considered one of the primary causes of cardiovascular diseases (CVDs).
Unpredictable rupture of the vulnerable atherosclerotic plaques triggers adverse …

Atherosclerosis Treatment with Stimuli‐Responsive Nanoagents: Recent Advances and Future Perspectives

A Maruf, Y Wang, T Yin, J Huang… - Advanced …, 2019 - Wiley Online Library
Atherosclerosis is the root of approximately one‐third of global mortalities. Nanotechnology
exhibits splendid prospects to combat atherosclerosis at the molecular level by engineering …

[HTML][HTML] Quince extract resists atherosclerosis in rats by down-regulating the EGFR/PI3K/Akt/GSK-3β pathway

A Abulizi, J Simayi, M Nuermaimaiti, M Han… - Biomedicine & …, 2023 - Elsevier
We identified the effective components and the underlying mechanisms of Quince (Cydonia
oblonga Mill, COM) extract against atherosclerosis. The effective components of COM …

The dual role of low-density lipoprotein receptor-related protein 1 in atherosclerosis

J Chen, Y Su, S Pi, B Hu, L Mao - Frontiers in cardiovascular …, 2021 - frontiersin.org
Low-density lipoprotein receptor–related protein-1 (LRP1) is a large endocytic and signaling
receptor belonging to the LDL receptor (LDLR) gene family and that is widely expressed in …

Inflammation, atherosclerosis, and coronary artery disease: PET/CT for the evaluation of atherosclerosis and inflammation

N Alie, M Eldib, ZA Fayad… - Clinical Medicine Insights …, 2014 - journals.sagepub.com
Atherosclerosis is a prevalent cardiovascular disease marked by inflammation and the
formation of plaque within arterial walls. As the disease progresses, there is an increased …

Tumor targeting of MMP-2/9 activatable cell-penetrating imaging probes is caused by tumor-independent activation

SMJ van Duijnhoven, MS Robillard… - Journal of Nuclear …, 2011 - Soc Nuclear Med
Activatable cell-penetrating peptides (ACPPs) are a new class of promising molecular
imaging probes for the visualization of enzymes in vivo. The cell-penetrating function of a …

Combined PET/MRI: multi-modality multi-parametric imaging is here: summary report of the 4th International Workshop on PET/MR Imaging; February 23–27, 2015 …

DL Bailey, BJ Pichler, B Gückel, H Barthel… - Molecular imaging and …, 2015 - Springer
This paper summarises key themes and discussions from the 4th international workshop
dedicated to the advancement of the technical, scientific and clinical applications of …

[HTML][HTML] Cell-penetrating peptides and their analogues as novel nanocarriers for drug delivery

S Jafari, SM Dizaj, K Adibkia - BioImpacts: BI, 2015 - ncbi.nlm.nih.gov
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Introduction: The impermeability of biological membranes is a major obstacle in drug …

Diabetic retinopathy and signaling mechanism for activation of matrix metalloproteinase‐9

G Mohammad, RA Kowluru - Journal of cellular physiology, 2012 - Wiley Online Library
In the pathogenesis of diabetic retinopathy, H‐Ras (a small molecular weight G‐protein) and
matrix metalloproteinase‐9 (MMP9) act as pro‐apoptotic, accelerating the apoptosis of …

Inflammation-targeted gold nanorods for intravascular photoacoustic imaging detection of matrix metalloproteinase-2 (MMP2) in atherosclerotic plaques

H Qin, Y Zhao, J Zhang, X Pan, S Yang… - … , Biology and Medicine, 2016 - Elsevier
Elevated expression of matrix metalloproteinase-2 (MMP 2) is one of the clinical features of
high-risk atherosclerotic plaques. Many methods such as fluorescence imaging methods …