• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Regulated cell death is a vital and dynamic process in multicellular organisms that maintains
tissue homeostasis and eliminates potentially dangerous cells. Apoptosis, one of the better …

Kardiomiopatie definiuje się jako strukturalne oraz funkcjonalne nieprawidłowości mięśnia
komór, które nie wynikają z niedokrwienia na skutek choroby wieńcowej czy …

Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal
endothelial dystrophy and the leading indication for corneal transplantation worldwide …

REVIEW Bcl-2 and related cytoplasmic proteins are key regulators of apoptosis, the cell
suicide program critical for development, tissue homeostasis, and protection against …

Uncontrolled cell proliferation is the hallmark of cancer, and tumor cells have typically
acquired damage to genes that directly regulate their cell cycles. Genetic alterations …

A cell-free system based on cytosols of normally growing cells is established that
reproduces aspects of the apoptotic program in vitro. The apoptotic program is initiated by …

Tremendous progress has been made in understanding the molecular basis of the antiviral
actions of interferons (IFNs), as well as strategies evolved by viruses to antagonize the …

In oncology, the term 'hyperthermia'refers to the treatment of malignant diseases by
administering heat in various ways. Hyperthermia is usually applied as an adjunct to an …

Cellular stress, particularly in response to toxic and metabolic insults that perturb function of
the endoplasmic reticulum (ER stress), is a powerful inducer of the transcription factor …