Roles of exosomes in the normal and diseased eye

M Klingeborn, WM Dismuke, CB Rickman… - Progress in retinal and …, 2017 - Elsevier
Exosomes are nanometer-sized vesicles that are released by cells in a controlled fashion
and mediate a plethora of extra-and intercellular activities. Some key functions of exosomes …

Perspectives of using microRNA-loaded nanocarriers for epigenetic reprogramming of drug resistant colorectal cancers

OA Sukocheva, J Liu, ME Neganova… - Seminars in Cancer …, 2022 - Elsevier
Epigenetic regulation by microRNAs (miRs) demonstrated a promising therapeutic potential
of these molecules to regulate genetic activity in different cancers, including colorectal …

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

J Van Deun, P Mestdagh, P Agostinis, Ö Akay… - Nature …, 2017 - nature.com
We argue that the field of extracellular vesicle (EV) biology needs more transparent
reporting to facilitate interpretation and replication of experiments. To achieve this, we …

Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine

B Dhondt, E Geeurickx, J Tulkens… - Journal of …, 2020 - Taylor & Francis
Extracellular vesicles (EV) are increasingly being recognized as important vehicles of
intercellular communication and promising diagnostic and prognostic biomarkers in cancer …

A functionalized collagen-I scaffold delivers microRNA 21-loaded exosomes for spinal cord injury repair

X Liu, L Zhang, Z Xu, X Xiong, Y Yu, H Wu, H Qiao… - Acta Biomaterialia, 2022 - Elsevier
MicroRNA (miRNA)-based therapies have shown great potential in the repair of spinal cord
injury (SCI). MicroRNA 21 (miR21) has been proven to have an essential protective effect on …

Exosomes: Their role in pathogenesis, diagnosis and treatment of diseases

H Aheget, L Mazini, F Martin, B Belqat, JA Marchal… - Cancers, 2020 - mdpi.com
Simple Summary The aim of this review is to provide an overview of the current scientific
evidence concerning the role played by exosomes in the pathogenesis, diagnosis and …

Mesenchymal stem cell-derived extracellular vesicles: An emerging diagnostic and therapeutic biomolecules for neurodegenerative disabilities

M Kandeel, MA Morsy, KM Alkhodair, S Alhojaily - Biomolecules, 2023 - mdpi.com
Mesenchymal stem cells (MSCs) are a type of versatile adult stem cells present in various
organs. These cells give rise to extracellular vesicles (EVs) containing a diverse array of …

Apoptotic vesicles regulate bone metabolism via the miR1324/SNX14/SMAD1/5 signaling axis

Y Zhu, K Yang, Y Cheng, Y Liu, R Gu, X Liu, H Liu… - Small, 2023 - Wiley Online Library
Mesenchymal stem cells (MSCs) are widely used in the treatment of diseases. After their in
vivo application, MSCs undergo apoptosis and release apoptotic vesicles (apoVs). This …

Extracellular vesicles-mediated noncoding RNAs transfer in cancer

P Ma, Y Pan, W Li, C Sun, J Liu, T Xu, Y Shu - Journal of hematology & …, 2017 - Springer
Extracellular vesicles (EVs) are small membranous vesicles secreted from numerous cell
types and have been found involved in cell-to-cell communication by transferring noncoding …

[HTML][HTML] Isolation and Identification of miRNAs in exosomes derived from serum of colon cancer patients

L Zhao, J Yu, J Wang, H Li, J Che, B Cao - Journal of Cancer, 2017 - ncbi.nlm.nih.gov
Objective: To isolate exosomes from the serum of colon cancer patients and identify RNAs in
the small vesicles. Methods: ExoQuick-TC™ Exosome Precipitation Solution was used for …