Atheroprotective Aspects of Heat Shock Proteins

AV Poznyak, VA Orekhova, VN Sukhorukov… - International Journal of …, 2023 - mdpi.com
Atherosclerosis is a major global health problem. Being a harbinger of a large number of
cardiovascular diseases, it ultimately leads to morbidity and mortality. At the same time …

[PDF][PDF] Anti-inflammatory and immunomodulatory therapies in atherosclerosis

J Deroissart, F Porsch, T Koller… - … and Treatment of …, 2021 - library.oapen.org
Hypercholesterolemia is a major risk factor in atherosclerosis development and lipid-
lowering drugs (ie, statins) remain the treatment of choice. Despite effective reduction of LDL …

Mining Autoimmune-Disorder-Linked Molecular-Mimicry Candidates in Clostridioides difficile and Prospects of Mimic-Based Vaccine Design: An In Silico Approach

S Alshamrani, MM Mashraqi, A Alzamami, NA Alturki… - Microorganisms, 2023 - mdpi.com
Molecular mimicry, a phenomenon in which microbial or environmental antigens resemble
host antigens, has been proposed as a potential trigger for autoimmune responses. In this …

Circulating antibodies against leukotoxin A as marker of periodontitis Grades B and C and oral infection with Aggregatibacter actinomycetemcomitans

C Damgaard, AK Danielsen, C Enevold… - Journal of …, 2021 - Wiley Online Library
Abstract Background The facultative bacterium Aggregatibacter actinomycetemcomitans
(Aa) is strongly associated with periodontitis and is occasionally found in periodontally …

Total fecal IgA levels increase and natural IgM antibodies decrease after gastric bypass surgery

N Istomin, MA Härma, R Akhi, AE Nissinen… - Apmis, 2022 - Wiley Online Library
Obesity is associated with low‐grade inflammation and increased systemic oxidative stress.
Roux‐en‐Y gastric bypass (RYGB) surgery is known to ameliorate the obesity‐induced …

Association between periodontal disease and coronary heart disease: A bibliometric analysis

W Song, X Bo, H Dou, Q Fan, H Wang - Heliyon, 2024 - cell.com
Background Periodontal disease and coronary heart disease are both prevalent diseases
worldwide and cause patients physical and mental suffering and a global burden. Recent …

[HTML][HTML] Compensatory IgM to the Rescue: Patients with Selective IgA Deficiency Have Increased Natural IgM Antibodies to MAA–LDL and No Changes in Oral …

MA Mella, A Lavrinienko, R Akhi, R Hindström… - …, 2021 - journals.aai.org
IgA is the most abundant Ab in the human body. However, most patients with selective IgA
deficiency (SIgAD) are asymptomatic. IgM, and to lesser extent IgG Abs, are generally …

Heat Shock Proteins and Periodontitis–Cross-Reaction Between Bacterial and Human HSP in Periodontal Infection Linking with Cardiovascular Diseases

T Yamamoto, T Eguchi - Heat shock proteins in inflammatory diseases, 2020 - Springer
Introduction Periodontitis is a globally prevalent chronic inflammatory disease caused by
oral dysbiotic biofilm. The host immune and inflammatory responses against the biofilm play …

Salivary IgA antibody to malondialdehyde–acetaldehyde associates with mild periodontal pocket depth

R Akhi, AE Nissinen, C Wang, M Kyrklund… - Oral …, 2022 - Wiley Online Library
Objective Oxidized epitopes such as malondialdehyde–acetaldehyde (MAA) play a crucial
role in the progression of atherosclerosis through activation of the humoral immune …

Aggregatibacter actinomycetemcomitans exploits and modulates the immune response by human neutrophils for survival in the anaerobic environment.

H Ozuna - 2022 - ir.library.louisville.edu
Aggregatibacter actinomycetemcomitans (Aa) is a Gram-negative facultative anaerobe and
an opportunistic oral pathogen, strongly associated with localized periodontitis and other …