Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures
Absence seizures in children and teenagers are generally considered relatively benign
because of their non-convulsive nature and the large incidence of remittance in early …
because of their non-convulsive nature and the large incidence of remittance in early …
[HTML][HTML] The guide to dendritic spikes of the mammalian cortex in vitro and in vivo
ME Larkum, J Wu, SA Duverdin, A Gidon - Neuroscience, 2022 - Elsevier
Half a century since their discovery by Llinás and colleagues, dendritic spikes have been
observed in various neurons in different brain regions, from the neocortex and cerebellum to …
observed in various neurons in different brain regions, from the neocortex and cerebellum to …
Dual function of thalamic low-vigilance state oscillations: rhythm-regulation and plasticity
During inattentive wakefulness and non-rapid eye movement (NREM) sleep, the neocortex
and thalamus cooperatively engage in rhythmic activities that are exquisitely reflected in the …
and thalamus cooperatively engage in rhythmic activities that are exquisitely reflected in the …
Dopamine inhibition differentially controls excitability of substantia nigra dopamine neuron subpopulations through T-type calcium channels
While there is growing appreciation for diversity among ventral tegmental area dopamine
neurons, much less is known regarding functional heterogeneity among the substantia nigra …
neurons, much less is known regarding functional heterogeneity among the substantia nigra …
Towards building a more complex view of the lateral geniculate nucleus: Recent advances in understanding its role
M Ghodrati, SM Khaligh-Razavi, SR Lehky - Progress in Neurobiology, 2017 - Elsevier
The lateral geniculate nucleus (LGN) has often been treated in the past as a linear filter that
adds little to retinal processing of visual inputs. Here we review anatomical …
adds little to retinal processing of visual inputs. Here we review anatomical …
The T‐type calcium channel antagonist, Z944, reduces spinal excitability and pain hypersensitivity
Background and Purpose T‐type voltage‐gated calcium channels are an emerging
therapeutic target for neurological disorders including epilepsy and pain. Inhibition of T‐type …
therapeutic target for neurological disorders including epilepsy and pain. Inhibition of T‐type …
Lack of intrinsic GABAergic connections in the thalamic reticular nucleus of the mouse
It is generally thought that neurons in the thalamic reticular nucleus (TRN) form GABAergic
synapses with other TRN neurons and that these interconnections are important for the …
synapses with other TRN neurons and that these interconnections are important for the …
The Ca2+-activated chloride channel anoctamin-2 mediates spike-frequency adaptation and regulates sensory transmission in thalamocortical neurons
Neuronal firing patterns, which are crucial for determining the nature of encoded information,
have been widely studied; however, the molecular identity and cellular mechanisms of spike …
have been widely studied; however, the molecular identity and cellular mechanisms of spike …
T-type calcium channels in synaptic plasticity
N Leresche, RC Lambert - Channels, 2017 - Taylor & Francis
The role of T-type calcium currents is rarely considered in the extensive literature covering
the mechanisms of long-term synaptic plasticity. This situation reflects the lack of suitable T …
the mechanisms of long-term synaptic plasticity. This situation reflects the lack of suitable T …
Distinct dendritic Ca2+ spike forms produce opposing input-output transformations in rat CA3 pyramidal cells
Proper integration of different inputs targeting the dendritic tree of CA3 pyramidal cells
(CA3PCs) is critical for associative learning and recall. Dendritic Ca 2+ spikes have been …
(CA3PCs) is critical for associative learning and recall. Dendritic Ca 2+ spikes have been …