Heart disease and stroke statistics—2019 update: a report from the American Heart Association

EJ Benjamin, P Muntner, A Alonso, MS Bittencourt… - Circulation, 2019 - Am Heart Assoc
Summary Each year, the American Heart Association (AHA), in conjunction with the National
Institutes of Health and other government agencies, brings together in a single document the …

Heart disease and stroke statistics—2018 update: a report from the American Heart Association

EJ Benjamin, SS Virani, CW Callaway… - Circulation, 2018 - Am Heart Assoc
Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …

Use of Lipoprotein (a) in clinical practice: A biomarker whose time has come. A scientific statement from the National Lipid Association

DP Wilson, TA Jacobson, PH Jones… - Journal of clinical …, 2019 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] is a well-recognized, independent risk factor for
atherosclerotic cardiovascular disease, with elevated levels estimated to be prevalent in …

NHLBI working group recommendations to reduce lipoprotein (a)-mediated risk of cardiovascular disease and aortic stenosis

S Tsimikas, S Fazio, KC Ferdinand… - Journal of the American …, 2018 - jacc.org
Pathophysiological, epidemiological, and genetic studies provide strong evidence that
lipoprotein (a)[Lp (a)] is a causal mediator of cardiovascular disease (CVD) and calcific …

Heart disease and stroke statistics—2020 update: a report from the American Heart Association

SS Virani, A Alonso, EJ Benjamin, MS Bittencourt… - Circulation, 2020 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports on the most up-to-date statistics related to heart disease, stroke …

[HTML][HTML] The Rotterdam Study: 2016 objectives and design update

A Hofman, GGO Brusselle, SD Murad… - European journal of …, 2015 - Springer
Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …

Big data analytics for genomic medicine

KY He, D Ge, MM He - International journal of molecular sciences, 2017 - mdpi.com
Genomic medicine attempts to build individualized strategies for diagnostic or therapeutic
decision-making by utilizing patients' genomic information. Big Data analytics uncovers …

PharmVar GeneFocus: SLCO1B1

LB Ramsey, L Gong, S Lee, JB Wagner… - Clinical …, 2023 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) is now providing star (*) allele
nomenclature for the highly polymorphic human SLCO1B1 gene encoding the organic anion …

Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin

K Zhou, SW Yee, EL Seiser, N Van Leeuwen… - Nature …, 2016 - nature.com
Metformin is the first-line antidiabetic drug with over 100 million users worldwide, yet its
mechanism of action remains unclear. Here the Metformin Genetics (MetGen) Consortium …

[HTML][HTML] Lipoprotein (a) beyond the kringle IV repeat polymorphism: the complexity of genetic variation in the LPA gene

S Coassin, F Kronenberg - Atherosclerosis, 2022 - Elsevier
Abstract High lipoprotein (a)[Lp (a)] concentrations are one of the most important genetically
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …