The mitochondrial oxidative phosphorylation system is central to cellular metabolism. It
comprises five enzymatic complexes and two mobile electron carriers that work in a …

The use of fossil fuels has been strongly related to critical problems currently affecting
society, such as: global warming, global greenhouse effects and pollution. These problems …

Mitochondrial energy conversion requires an intricate architecture of the inner mitochondrial
membrane. Here we show that a supercomplex containing all four respiratory chain …

The respiratory megacomplex represents the highest-order assembly of respiratory chain
complexes, and it allows mitochondria to respond to energy-requiring conditions. To …

Biological energy conversion in mitochondria is carried out by the membrane protein
complexes of the respiratory chain and the mitochondrial ATP synthase in the inner …

Mitochondrial electron transport chain complexes are organized into supercomplexes
responsible for carrying out cellular respiration. Here we present three architectures of …

Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

The oxidative phosphorylation electron transport chain (OXPHOS-ETC) of the inner
mitochondrial membrane is composed of five large protein complexes, named CI–CV. These …

Abstract Knowledge of the three-dimensional structures of proteins and other biological
macromolecules often aids understanding of how they perform complicated tasks in the cell …

Transient receptor potential (TRP) channels are sensors for a wide range of cellular and
environmental signals, but elucidating how these channels respond to physical and …