Solid-state NMR: Methods for biological solids
S Ahlawat, KR Mote, NA Lakomek… - Chemical Reviews, 2022 - ACS Publications
In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …
transformed from a spectroscopic technique investigating small molecules and industrial …
Perturbations of native membrane protein structure in alkyl phosphocholine detergents: a critical assessment of NMR and biophysical studies
Membrane proteins perform a host of vital cellular functions. Deciphering the molecular
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …
Chemical shift tensor–The heart of NMR: Insights into biological aspects of proteins
H Saitô, I Ando, A Ramamoorthy - Progress in nuclear magnetic resonance …, 2010 - Elsevier
The chemical shift of a nucleus, i, in a molecule arises from the nuclear shielding effect of an
applied magnetic field, caused by an induced magnetic field resulting from circulation of …
applied magnetic field, caused by an induced magnetic field resulting from circulation of …
α-Helical transmembrane peptides: a “divide and conquer” approach to membrane proteins
N Bordag, S Keller - Chemistry and physics of lipids, 2010 - Elsevier
α-Helical membrane proteins fulfill many vital roles in all living cells and constitute the
majority of drug targets. However, their relevance is in no way paralleled by our current …
majority of drug targets. However, their relevance is in no way paralleled by our current …
Mapping the interaction surface of a membrane protein: unveiling the conformational switch of phospholamban in calcium pump regulation
J Zamoon, F Nitu, C Karim… - Proceedings of the …, 2005 - National Acad Sciences
We have used magnetic resonance to map the interaction surface of an integral membrane
protein for its regulatory target, an integral membrane enzyme. Phospholamban (PLN) …
protein for its regulatory target, an integral membrane enzyme. Phospholamban (PLN) …
Membrane Proteins II: 3D Structure
H Saitô, I Ando, A Naito - Solid State NMR Spectroscopy for Biopolymers …, 2006 - Springer
The general approach for obtaining NMR constraints essential for determination of 3D
structure of proteins as well as its theoretical background were already discussed in Section …
structure of proteins as well as its theoretical background were already discussed in Section …
Investigations of the structure, topology, and interactions of the transmembrane domain of the lipid-sorting protein p24 being highly selective for sphingomyelin-C18
C Aisenbrey, P Kemayo-Koumkoua, ES Salnikov… - Biochemistry, 2019 - ACS Publications
The p24 proteins play an important role in the secretory pathway where they selectively
connect various cargo to other proteins, thereby being involved in the controlled assembly …
connect various cargo to other proteins, thereby being involved in the controlled assembly …
Rational design of peptide inhibitors of the sarcoplasmic reticulum calcium pump
MR Afara, CA Trieber, JP Glaves, HS Young - Biochemistry, 2006 - ACS Publications
The sequence of phospholamban (PLB) is practically invariant among mammalian species.
The hydrophobic transmembrane domain has 10 leucine and 8 isoleucine residues. Two …
The hydrophobic transmembrane domain has 10 leucine and 8 isoleucine residues. Two …
Secondary structure, backbone dynamics, and structural topology of phospholamban and its phosphorylated and Arg9Cys-mutated forms in phospholipid bilayers …
X Yu, GA Lorigan - The Journal of Physical Chemistry B, 2014 - ACS Publications
Phospholamban (PLB) is a membrane protein that regulates heart muscle relaxation rates
via interactions with the sarcoplasmic reticulum Ca2+ ATPase (SERCA). When PLB is …
via interactions with the sarcoplasmic reticulum Ca2+ ATPase (SERCA). When PLB is …
The structural topology of wild‐type phospholamban in oriented lipid bilayers using 15N solid‐state NMR spectroscopy
S Abu‐Baker, JX Lu, S Chu, KK Shetty… - Protein …, 2007 - Wiley Online Library
For the first time, 15N solid‐state NMR experiments were conducted on wild‐type
phospholamban (WT‐PLB) embedded inside mechanically oriented phospholipid bilayers …
phospholamban (WT‐PLB) embedded inside mechanically oriented phospholipid bilayers …