Molecular and ionic diffusion in ion exchange membranes and biological systems (Cells and proteins) studied by NMR

VI Volkov, AV Chernyak, IA Avilova, NA Slesarenko… - Membranes, 2021 - mdpi.com
The results of NMR, and especially pulsed field gradient NMR (PFG NMR) investigations,
are summarized. Pulsed field gradient NMR technique makes it possible to investigate …

A Magnetic Resonance Imaging‐Chemical Exchange Saturation Transfer (MRI‐CEST) Method for the Detection of Water Cycling across Cellular Membranes

E Di Gregorio, C Papi, L Conti, A Di Lorenzo… - Angewandte …, 2024 - Wiley Online Library
Water cycling across the membrane transporters is considered a hallmark of cellular
metabolism and it could be of high diagnostic relevance in the characterization of tumors …

Development of icephilic ACTIVE glycopeptides for cryopreservation of human erythrocytes

S Gao, K Zhu, Q Zhang, Q Niu, J Chong, L Ren… - …, 2021 - ACS Publications
Ice formation and recrystallization exert severe impairments to cellular cryopreservation. In
light of cell-damaging washing procedures in the current glycerol approach, many …

Evidence for the role of intracellular water lifetime as a tumour biomarker obtained by in vivo field‐cycling relaxometry

MR Ruggiero, S Baroni, S Pezzana… - Angewandte …, 2018 - Wiley Online Library
It was established through in vivo T1 measurements at low magnetic fields that tumour cells
display proton T1 values that are markedly longer than those shown by healthy tissue …

Apatite nanoparticles strongly improve red blood cell cryopreservation by mediating trehalose delivery via enhanced membrane permeation

M Stefanic, K Ward, H Tawfik, R Seemann, V Baulin… - Biomaterials, 2017 - Elsevier
Cryopreservation of red blood cells (RBC) is an important method for maintaining an
inventory of rare RBC units and managing special transfusion circumstances. Currently, in a …

Integration of trehalose lipids with dissociative trehalose enables cryopreservation of human RBCs

Y Wang, S Gao, K Zhu, L Ren… - ACS Biomaterials Science …, 2022 - ACS Publications
Cryopreservation of red blood cells (RBCs) is imperative for transfusion therapy, while
cryoprotectants are essential to protect RBCs from cryoinjury under freezing temperatures …

NMR quantification of diffusional exchange in cell suspensions with relaxation rate differences between intra and extracellular compartments

S Eriksson, K Elbing, O Söderman… - PloS one, 2017 - journals.plos.org
Water transport across cell membranes can be measured non-invasively with diffusion NMR.
We present a method to quantify the intracellular lifetime of water in cell suspensions with …

Facilitating trehalose entry into hRBCs at 4° C by alkylated ε-poly (l-lysine) for glycerol-free cryopreservation

X Liu, S Gao, Q Niu, K Zhu, L Ren… - Journal of Materials …, 2022 - pubs.rsc.org
Currently, glycerol is a conventional cryoprotectant of human red blood cells (hRBCs), but
the time-consuming thawing and deglycerolization processes are essential before …

Membrane stabilization versus perturbation by aromatic monoamine-modified γ-PGA for cryopreservation of human RBCs with high intracellular trehalose

Q Niu, S Gao, X Liu, J Chong, L Ren, K Zhu… - Journal of Materials …, 2022 - pubs.rsc.org
As a nonreducing disaccharide, trehalose can be used as a biocompatible cryoprotectant for
solvent-free cell cryopreservation, but the membrane-impermeability limits its cryoprotective …

Cryopreservation of human erythrocytes through high intracellular trehalose with membrane stabilization of maltotriose-grafted ε-poly (L-lysine)

S Gao, Q Niu, X Liu, C Zhu, J Chong, L Ren… - Journal of Materials …, 2022 - pubs.rsc.org
Cryopreservation of human erythrocytes via suitable cryoprotectants is essential for
transfusion during emergencies, but the conventional glycerolization method requires a …