Mobile genetic elements are key to the evolution of bacteria and traits that affect host and
ecosystem health. Here, we use a framework of a hierarchical and modular system that …

Antimicrobial resistance (AMR) is one of the Global Health challenges of the 21st century.
The inclusion of AMR on the global map parallels the scientific, technological, and …

Bacterial conjugation mediates contact-dependent transfer of DNA from donor to recipient
bacteria, thus facilitating the spread of virulence and resistance plasmids. Here we describe …

Whole-genome sequencing of antimicrobial-resistant pathogens is increasingly being used
for antimicrobial resistance (AMR) surveillance, particularly in high-income countries …

Infections caused by metallo-beta-lactamase-producing organisms (MBLs) are a global
health threat. Our understanding of transmission dynamics and how MBLs establish …

ABSTRACT From January 2019 to April 2020, 32 KPC-producing, ceftazidime-avibactam
(CZA)-resistant Klebsiella pneumoniae strains were isolated in a university hospital in …

For people living in developed countries life span is growing at a faster pace than ever. One
of the main reasons for such success is attributable to the introduction and extensive use in …

Background Klebsiella pneumoniae is a notorious clinical pathogen and frequently carries
various plasmids, which are the main carriers of antimicrobial resistance and virulence …

Introduction National and regional carbapenemase-producing Enterobacterales (CPE)
surveillance is essential to understand the burden of antimicrobial resistance, elucidate …

Carbapenem resistant Enterobacteriaceae (CRE) are a threat to public health globally, yet
the role of the environment in the epidemiology of CRE remains elusive. Given that wild …