Bone physiology as inspiration for tissue regenerative therapies

D Lopes, C Martins-Cruz, MB Oliveira, JF Mano - Biomaterials, 2018 - Elsevier
The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …

Surface modification of biomaterials and biomedical devices using additive manufacturing

S Bose, SF Robertson, A Bandyopadhyay - Acta biomaterialia, 2018 - Elsevier
The demand for synthetic biomaterials in medical devices, pharmaceutical products and,
tissue replacement applications are growing steadily due to aging population worldwide …

Multifunctional coatings and nanotopographies: toward cell instructive and antibacterial implants

C Mas‐Moruno, B Su, MJ Dalby - Advanced healthcare …, 2019 - Wiley Online Library
In biomaterials science, it is nowadays well accepted that improving the biointegration of
dental and orthopedic implants with surrounding tissues is a major goal. However, implant …

Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency

RJ McMurray, N Gadegaard, PM Tsimbouri… - Nature materials, 2011 - nature.com
There is currently an unmet need for the supply of autologous, patient-specific stem cells for
regenerative therapies in the clinic. Mesenchymal stem cell differentiation can be driven by …

Bactericidal effects of nanopatterns: A systematic review

K Modaresifar, S Azizian, M Ganjian… - Acta biomaterialia, 2019 - Elsevier
We systematically reviewed the currently available evidence on how the design parameters
of surface nanopatterns (eg height, diameter, and interspacing) relate to their bactericidal …

Impact of surface topography and coating on osteogenesis and bacterial attachment on titanium implants

L Damiati, MG Eales, AH Nobbs, B Su… - Journal of Tissue …, 2018 - journals.sagepub.com
Titanium (Ti) plays a predominant role as the material of choice in orthopaedic and dental
implants. Despite the majority of Ti implants having long-term success, premature failure due …

Functionalized TiO2 Based Nanomaterials for Biomedical Applications

S Wu, Z Weng, X Liu, KWK Yeung… - Advanced functional …, 2014 - Wiley Online Library
As baby boomers age, diabetes mellitus, cancer, osteoarthritis, cardiovascular diseases,
and orthopedic disorders are more widespread and the demand for better biomedical …

The roles of titanium surface micro/nanotopography and wettability on the differential response of human osteoblast lineage cells

RA Gittens, R Olivares-Navarrete, A Cheng… - Acta biomaterialia, 2013 - Elsevier
Surface micro-and nanostructural modifications of dental and orthopedic implants have
shown promising in vitro, in vivo and clinical results. Surface wettability has also been …

An overview of recent advances in designing orthopedic and craniofacial implants

VP Mantripragada, B Lecka‐Czernik… - … research Part A, 2013 - Wiley Online Library
Great deal of research is still going on in the field of orthopedic and craniofacial implant
development to resolve various issues being faced by the industry today. Despite several …

Influence of surface topographical cues on the differentiation of mesenchymal stem cells in vitro

K Metavarayuth, P Sitasuwan, X Zhao… - ACS Biomaterials …, 2016 - ACS Publications
Adult stem cell research has been advanced in recent years because of the cells' attractive
abilities of self-renewal and differentiation. Topography of materials is one of the key …