Glomerulonephritis (GN) is an important cause of morbidity and mortality in patients of all
ages throughout the world. Because these disorders are relatively rare, it is difficult to …

Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

In Japan, original researches on nephrotic syndrome (NS) were initially performed by the
Ministry of Health, Labour and Welfare (MHLW) NS research group. The first definition of NS …

Minimal-change disease (MCD) counts for 10 to 15% of cases of primary nephrotic
syndrome in adults. Few series have examined this disease in adults. A retrospective review …

Minimal change disease (MCD) is the etiology of 10%–25% of cases of nephrotic syndrome
in adults. The mainstay of treatment for adult MCD, oral gucocorticoids, is based on two …

Results There were no significant differences between the tacrolimus and prednisolone
treatment cohorts in the proportion of patients in complete remission at 8 weeks (21 out of 25 …

Introduction. Minimal change nephrotic syndrome (MCNS) is a common form of nephrotic
syndrome in children and young adults. We investigated its clinical presentations, steroid …

Background Few studies have examined the treatment and outcome of adult-onset minimal
change nephrotic syndrome (MCNS). We retrospectively studied 125 patients who had …

Background Minimal change disease (MCD) is a common cause of the nephrotic syndrome
in adults with limited evidence on its treatment and prognosis. We examined the presenting …

Background Tacrolimus is used as a steroid-sparing immunosuppressant in adults with
minimal change nephrotic syndrome. However, combined treatment with tacrolimus and low …