Surgical management of primary severe hypospadias in children: an update focusing on penile curvature

M Castagnetti, A El-Ghoneimi - Nature Reviews Urology, 2022 - nature.com
Over the past two decades, assessment and treatment of associated curvature has emerged
as a major issue in treating patients with proximal hypospadias. However, the cut-off for …

Adolescent and young adult urogenital outcome following childhood hypospadias repair: perfection revisited

LJW Tack, A Springer, S Riedl, U Tonnhofer… - The Journal of …, 2021 - auajournals.org
Purpose: We assessed the long-term surgical, functional urinary and sexual outcomes of
adolescent and young adult men who underwent childhood hypospadias repair. Materials …

Grade of hypospadias is the only factor predicting for re-intervention after primary hypospadias repair: a multivariate analysis from a cohort of 474 patients

AF Spinoit, F Poelaert, C Van Praet, LA Groen… - Journal of pediatric …, 2015 - Elsevier
Background There is an ongoing quest on how to minimize complications in hypospadias
surgery. There is however a lack of high-quality data on the following parameters that might …

Preoperative glans & penile dimensions in different hypospadias grades

M Sennert, J Wirmer, AT Hadidi - Journal of Pediatric Urology, 2022 - Elsevier
Purpose To report glans and penile dimensions in 1023 consecutive boys with hypospadias.
Patients & methods Boys admitted for hypospadias surgery between 2016 and 2018 were …

Abnormal dartos fascia in buried penis and hypospadias: Evidence from histopathology

W Atmoko, G Shalmont, GR Situmorang… - Journal of Pediatric …, 2018 - Elsevier
Introduction The importance of the pathology of the dartos fascia in hypospadias and buried
penis is still debatable. Understanding the properties of connective tissue of dartos fascia in …

Buried penis surgical treatment in children: Dorsal dartos flap VS. Fascia fixation. A retrospective cohort study

C Delgado-Miguel, A Muñoz-Serrano, V Amesty… - Journal of Pediatric …, 2022 - Elsevier
Introduction Several surgical techniques for buried penis (BP) treatment have been
described, although there is not a reference pattern for it. In our institution, we have …

Androgen receptor expression in preputial dartos tissue correlates with physiological androgen exposure in congenital malformations of the penis and in controls

LJW Tack, M Praet, J Van Dorpe, B Haid… - Journal of Pediatric …, 2020 - Elsevier
Introduction The androgen receptor (AR) plays an important role in the development of male
genitalia, and impaired androgen signalling has been hypothesised to underlie congenital …

Comprehensive multidisciplinary phenotyping of patients with hypospadias. A pilot study

N Fernandez, A Maxwell, M Noonavath… - Journal of Pediatric …, 2023 - Elsevier
Introduction Hypospadias is an abnormal formation of the urethra, ventral skin, and corporal
bodies. Location of the urethral meatus has historically been the phenotypic landmark that …

The impact of COL1A1 and COL6A1 expression on hypospadias and penile curvature severity

P Yuri, Gunadi, RP Lestari, FP Fardilla… - BMC urology, 2020 - Springer
Background Hypospadias, the most frequent congenital male external genitalia abnormality,
is usually associated with curvature of the ventral penis, ie chordee. Abnormality of darto …

FGF8, FGF10 and FGF receptor 2 in foreskin of children with hypospadias: an analysis of immunohistochemical expression patterns and gene transcription

B Haid, E Pechriggl, F Nägele, J Dudas… - Journal of Pediatric …, 2020 - Elsevier
Summary Introduction Fibroblast growth factors (FGFs) play a crucial role in early
embryogenesis of the genital tubercle and are involved in the development of hypospadias …