Candida albicans is the most common pathogen causing clinical Candida infections.
Neutrophils are a key member of the host innate immunity that plays an essential role in …

The first description of a new form of neutrophil cell death distinct from that of apoptosis or
necrosis was discovered in 2004 and coined neutrophil extracellular traps “(NETs)” or …

Candida albicans is a fungal pathobiont, able to cause epithelial cell damage and immune
activation. These functions have been attributed to its secreted toxin, candidalysin, though …

Interleukin-17 (IL-17) is a proinflammatory cytokine produced by adaptive CD4+ T helper
cells and innate lymphocytes, such as γδ-T cells and TCRβ+“natural” Th17 cells. IL-17 …

Polymicrobial infections often include both fungi and bacteria and can complicate patient
treatment and resolution of infection. Cross-kingdom interactions among bacteria, fungi …

The specific roles of the two major innate immune cell types–neutrophils and macrophages–
in response to infection and sterile inflammation are areas of great interest. The larval …

The zebrafish has become a widely accepted model host for studies of infectious disease,
including fungal infections. The species is genetically tractable, and the larvae are …

Assessing the safety of engineered nanomaterials (NMs) is paramount to the responsible
and sustainable development of nanotechnology, which provides huge societal benefits …

Fungal infections are global public health problems and can lead to substantial human
morbidity and mortality. Current antifungal therapy is not satisfactory, especially for invasive …

The discovery, in 2004, of extracellular traps released by neutrophils has extended our
understanding of the mode of action of various innate immune cells. This fascinating …