The contribution of wildlife hosts to the rise of ticks and tick-borne diseases in North America

JI Tsao, SA Hamer, S Han, JL Sidge… - Journal of medical …, 2021 - academic.oup.com
Wildlife vertebrate hosts are integral to enzootic cycles of tick-borne pathogens, and in some
cases have played key roles in the recent rise of ticks and tick-borne diseases in North …

Whole genome sequencing of human Borrelia burgdorferi isolates reveals linked blocks of accessory genome elements located on plasmids and associated with …

JE Lemieux, W Huang, N Hill, T Cerar… - PLoS …, 2023 - journals.plos.org
Lyme disease is the most common vector-borne disease in North America and Europe. The
clinical manifestations of Lyme disease vary based on the genospecies of the infecting …

Complement evasion contributes to Lyme Borreliae–host associations

YP Lin, MA Diuk-Wasser, B Stevenson, P Kraiczy - Trends in parasitology, 2020 - cell.com
Lyme disease is the most common vector-borne disease in the northern hemisphere and is
caused by spirochetes of the Borrelia burgdorferi sensu lato complex. Lyme borreliae infect …

Structural evolution of an immune evasion determinant shapes pathogen host tropism

AL Marcinkiewicz, K Brangulis… - Proceedings of the …, 2023 - National Acad Sciences
Modern infectious disease outbreaks often involve changes in host tropism, the preferential
adaptation of pathogens to specific hosts. The Lyme disease-causing bacterium Borrelia …

Phylogeographic reconstruction of the emergence and spread of Powassan virus in the northeastern United States

CBF Vogels, DE Brackney, AP Dupuis… - Proceedings of the …, 2023 - National Acad Sciences
Powassan virus is an emerging tick-borne virus of concern for public health, but very little is
known about its transmission patterns and ecology. Here, we expanded the genomic dataset …

What is the real number of Lyme disease cases in Canada?

NH Ogden, C Bouchard, J Badcock, MA Drebot… - BMC Public Health, 2019 - Springer
Background Lyme disease is emerging in Canada due to expansion of the range of the tick
vector Ixodes scapularis from the United States. National surveillance for human Lyme …

Natural selection and recombination at host-interacting lipoprotein loci drive genome diversification of Lyme disease and related bacteria

S Akther, EF Mongodin, RD Morgan, L Di, X Yang… - MBio, 2024 - journals.asm.org
Lyme disease, caused by spirochetes in the Borrelia burgdorferi sensu lato clade within the
Borrelia genus, is transmitted by Ixodes ticks and is currently the most prevalent and rapidly …

Genospecies of Borrelia burgdorferi sensu lato detected in 16 mammal species and questing ticks from northern Europe

A Mysterud, VM Stigum, RI Jaarsma, H Sprong - Scientific reports, 2019 - nature.com
Lyme borreliosis is the most common vector-borne zoonosis in the northern hemisphere,
and the pathogens causing Lyme borreliosis have distinct, incompletely described …

Out of Asia? Expansion of Eurasian Lyme borreliosis causing genospecies display unique evolutionary trajectories

RE Rollins, K Sato, M Nakao, MT Tawfeeq… - Molecular …, 2023 - Wiley Online Library
Vector‐borne pathogens exist in obligate transmission cycles between vector and reservoir
host species. Host and vector shifts can lead to geographic expansion of infectious agents …

Cellular and immunological mechanisms influence host-adapted phenotypes in a vector-borne microparasite

YP Lin, DM Tufts, M Combs… - … of the Royal …, 2022 - royalsocietypublishing.org
Predicting pathogen emergence and spillover risk requires understanding the determinants
of a pathogens' host range and the traits involved in host competence. While host …