Role of diet and its effects on the gut microbiome in the pathophysiology of mental disorders

J Horn, DE Mayer, S Chen, EA Mayer - Translational psychiatry, 2022 - nature.com
There is emerging evidence that diet has a major modulatory influence on brain-gut-
microbiome (BGM) interactions with important implications for brain health, and for several …

[HTML][HTML] COVID-19 in pregnancy: implications for fetal brain development

LL Shook, EL Sullivan, JO Lo, RH Perlis… - Trends in molecular …, 2022 - cell.com
The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
during pregnancy on the developing fetal brain is poorly understood. Other antenatal …

Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring

AI Lim, T McFadden, VM Link, SJ Han, RM Karlsson… - Science, 2021 - science.org
INTRODUCTION One fundamental property of the immune system is its ability to develop
memory of previous encounters, resulting in enhanced responsiveness to subsequent …

Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications

CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

Interactions between the microbiota, immune and nervous systems in health and disease

TC Fung, CA Olson, EY Hsiao - Nature neuroscience, 2017 - nature.com
The diverse collection of microorganisms that inhabit the gastrointestinal tract, collectively
called the gut microbiota, profoundly influences many aspects of host physiology, including …

Microbiome-wide association studies link dynamic microbial consortia to disease

JA Gilbert, RA Quinn, J Debelius, ZZ Xu, J Morton… - Nature, 2016 - nature.com
Rapid advances in DNA sequencing, metabolomics, proteomics and computational tools are
dramatically increasing access to the microbiome and identification of its links with disease …

The influence of neuroinflammation in Autism Spectrum Disorder

SM Matta, EL Hill-Yardin, PJ Crack - Brain, behavior, and immunity, 2019 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterised
by deficits in social communication and restricted or repetitive behaviours. The clinical …

Control of brain development, function, and behavior by the microbiome

TR Sampson, SK Mazmanian - Cell host & microbe, 2015 - cell.com
Animals share an intimate and life-long partnership with a myriad of resident microbial
species, collectively referred to as the microbiota. Symbiotic microbes have been shown to …

Autism spectrum disorders: etiology and pathology

AK Sauer, J Stanton, S Hans… - Exon Publications, 2021 - exonpublications.com
Autism spectrum disorders (ASD) are a group of neurodevelopmental diseases. The cause
of ASD is unknown, but several genetic and non-genetic risk factors have been …

Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia

JC Cronk, AJ Filiano, A Louveau, I Marin… - Journal of Experimental …, 2018 - rupress.org
Peripherally derived macrophages infiltrate the brain after bone marrow transplantation and
during central nervous system (CNS) inflammation. It was initially suggested that these …