Brain activity is associated with changes in optical properties of brain tissue. Optical
measurements during brain activation can assess haemoglobin oxygenation, cytochrome-c …

The cerebral vascular system services the constant demand for energy during neuronal
activity in the brain. Attempts to delineate the logic of neurovascular coupling have been …

Cerebral blood flow (CBF) and cerebral autoregulation (CA) are critically important to
maintain proper brain perfusion and supply the brain with the necessary oxygen and energy …

A method for dynamic, high-resolution cerebral blood flow (CBF) imaging is presented in this
article. By illuminating the cortex with laser light and imaging the resulting speckle pattern …

Background and Purpose Acute cerebral ischemia after subarachnoid hemorrhage (SAH) is
a major cause of morbidity whose precise etiology is unclear. The purpose of this study was …

Intravenous tissue plasminogen activator (tPA) is used to treat acute stroke because of its
thrombolytic activity and its ability to restore circulation to the brain1, 2. However, this …

Anesthesia has broad actions that include changing neuronal excitability, vascular reactivity,
and other baseline physiologies and eventually modifies the neurovascular coupling …

Acute neutrophil (PMN) recruitment to postischemic cardiac or pulmonary tissue has
deleterious effects in the early reperfusion period, but the mechanisms and effects of …

Abstract BRAIN RETRACTION IS required for adequate exposure during many intracranial
procedures. The incidence of contusion or infarction from overzealous brain retraction is …

Modern functional neuroimaging methods, such as positron-emission tomography (PET),
optical imaging of intrinsic signals, and functional MRI (fMRI) utilize activity-dependent …