Comparative analysis of the chemical and biochemical synthesis of keto acids

Z Luo, S Yu, W Zeng, J Zhou - Biotechnology advances, 2021 - Elsevier
Keto acids are essential organic acids that are widely applied in pharmaceuticals,
cosmetics, food, beverages, and feed additives as well as chemical synthesis. Currently …

Production of α‐ketobutyrate using engineered Escherichia coli via temperature shift

C Zhang, J Qi, Y Li, X Fan, Q Xu… - Biotechnology and …, 2016 - Wiley Online Library
Alpha‐ketobutyrate has been widely used in medicine and food additive industry. Because
chemical and enzymatic methods are associated with many deficiencies, the recent focus …

Biotransformation of 3-cyanopyridine to nicotinic acid by free and immobilized cells of recombinant Escherichia coli

O Pai, L Banoth, S Ghosh, Y Chisti, UC Banerjee - Process Biochemistry, 2014 - Elsevier
An efficient biocatalytic process for the production of nicotinic acid (niacin) from 3-
cyanopyridine was developed using cells of recombinant Escherichia coli JM109 harboring …

Development of ratiometric fluorescence sensors based on CdSe/ZnS quantum dots for the detection of hydrogen peroxide

HD Duong, JI Rhee - Sensors, 2019 - mdpi.com
In this study, carboxyl group functionalized-CdSe/ZnS quantum dots (QDs) and
aminofluorescein (AF)-encapsulated polymer particles were synthesized and immobilized to …

Efficient Biosynthesis of (R)‐ or (S)‐2‐Hydroxybutyrate from l‐Threonine through a Synthetic Biology Approach

P Yao, Y Cui, S Yu, Y Du, J Feng… - Advanced Synthesis & …, 2016 - Wiley Online Library
An efficient multi‐enzyme cascade reaction for the synthesis of (R)‐or (S)‐2‐hydroxybutyric
acid [(R)‐or (S)‐2‐HB] from l‐threonine was developed by using recombinant Escherichia …

Genome-scale reconstruction of the metabolic network in Pseudomonas stutzeri A1501

P Babaei, SA Marashi, S Asad - Molecular BioSystems, 2015 - pubs.rsc.org
Pseudomonas stutzeri A1501 is an endophytic bacterium capable of nitrogen fixation. This
strain has been isolated from the rice rhizosphere and provides the plant with fixed nitrogen …

Metabolic Detoxification of 2-Oxobutyrate by Remodeling Escherichia coli Acetate Bypass

Y Fang, S Zhang, J Wang, L Yin, H Zhang, Z Wang… - Metabolites, 2021 - mdpi.com
2-Oxobutyrate (2-OBA), as a toxic metabolic intermediate, generally arrests the cell growth of
most microorganisms and blocks the biosynthesis of target metabolites. In this study, we …

Quality control by trans-editing factor prevents global mistranslation of non-protein amino acid α-aminobutyrate

JM Bacusmo, AB Kuzmishin, WA Cantara, Y Goto… - RNA biology, 2018 - Taylor & Francis
Accuracy in protein biosynthesis is maintained through multiple pathways, with a critical
checkpoint occurring at the tRNA aminoacylation step catalyzed by aminoacyl-tRNA …

A novel biocatalyst for efficient production of 2-oxo-carboxylates using glycerol as the cost-effective carbon source

Y Wang, Y Zhang, T Jiang, J Meng, B Sheng… - Biotechnology for …, 2015 - Springer
Background The surplus of glycerol has increased remarkably as a main byproduct during
the biofuel's production. Exploiting an alternative route for glycerol utilization is significantly …

Highly efficient production of 2-ketobutyrate from 2-hydroxybutyrate by resting cells of Pseudomonas stutzeri DEH130

Y Wang, Y Feng, S Xue - Biocatalysis and Biotransformation, 2016 - Taylor & Francis
Resting cells of Pseudomonas stutzeri DEH130 were found to act as biocatalysts to convert
2-hydroxybutyrate (2-HB) into 2-ketobutyrate (2-KA). Two different catalysis mechanisms of 2 …