Impact of retinoic acid on immune cells and inflammatory diseases

LM Oliveira, FME Teixeira… - Mediators of inflammation, 2018 - Wiley Online Library
Vitamin A metabolite retinoic acid (RA) plays important roles in cell growth, differentiation,
organogenesis, and reproduction and a key role in mucosal immune responses. RA …

[HTML][HTML] Retinoic acid, leaky gut, and autoimmune diseases

L Abdelhamid, XM Luo - Nutrients, 2018 - mdpi.com
A leaky gut has been observed in a number of autoimmune diseases including type 1
diabetes, multiple sclerosis, inflammatory bowel disease, and systemic lupus …

Mega doses of retinol: A possible immunomodulation in Covid‐19 illness in resource‐limited settings

IK Midha, N Kumar, A Kumar… - Reviews in medical …, 2021 - Wiley Online Library
Of all the nutrients, vitamin A has been the most extensively evaluated for its impact on
immunity. There are three main forms of vitamin A, retinol, retinal and retinoic acid (RA) with …

[HTML][HTML] Chemokine receptor 5 antagonism causes reduction in joint inflammation in a collagen-induced arthritis mouse model

MA Ansari, A Nadeem, SA Bakheet, SM Attia, M Shahid… - Molecules, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory disease mainly affecting the synovial
joints. A highly potent antagonist of CC chemokine receptor 5 (CCR5), maraviroc (MVC) …

[HTML][HTML] The role of retinoic acid in the production of immunoglobulin A

A Bos, M van Egmond, R Mebius - Mucosal Immunology, 2022 - Elsevier
Vitamin A and its derivative retinoic acid (RA) play important roles in the regulation of
mucosal immunity. The effect of vitamin A metabolism on T lymphocyte immunity has been …

B cells in chronic graft-versus-host disease

W McManigle, A Youssef, S Sarantopoulos - Human immunology, 2019 - Elsevier
Allogeneic hematopoietic stem cell transplantation (alloHCT) is the definitive therapy for
numerous otherwise incurable hematologic malignancies and non-malignant diseases. The …

Malaria, Epstein–Barr virus infection and the pathogenesis of Burkitt's lymphoma

AR Mawson, S Majumdar - International journal of cancer, 2017 - Wiley Online Library
A geographical and causal connection has long been recognized between malaria, Epstein–
Barr virus (EBV) infection and Burkitt's lymphoma (BL), but the underlying mechanisms …

[HTML][HTML] Sex differences in Tfh cell help to B cells contribute to sexual dimorphism in severity of rat collagen-induced arthritis

M Dimitrijević, N Arsenović-Ranin, D Kosec, B Bufan… - Scientific reports, 2020 - nature.com
The study examined germinal centre (GC) reaction in lymph nodes draining inflamed joints
and adjacent tissues (dLNs) in male and female Dark Agouti rat collagen type II (CII) …

An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD

JC Poe, W Jia, H Su, S Anand, JJ Rose… - Blood, The Journal …, 2017 - ashpublications.org
Abstract B-cell receptor (BCR)-activated B cells contribute to pathogenesis in chronic graft-
versus-host disease (cGVHD), a condition manifested by both B-cell autoreactivity and …

[HTML][HTML] Nano-encapsulated antioxidant: retinoic acid as a natural mucosal adjuvant for intranasal immunization against chronic experimental toxoplasmosis

DE Said, EI Amer, E Sheta, S Makled, FM Arafa… - Tropical Medicine and …, 2023 - mdpi.com
The tight relationship between immunity and retinoid levels provides evidence on the critical
role of retinoic acid (RA) in regulating immune activity, especially the mucosal one. Mucosal …