Fetal alcohol spectrum disorders (FASD) are a group of conditions associated with the
effects of prenatal alcohol exposure and characterized by somatic and neuropsychological …

Programmed cell death (apoptosis) occurs during normal development of the central
nervous system. However, the mechanisms that determine which neurons will succumb to …

Accumulating evidence indicates that the fetal environment plays an important role in brain
development and sets the brain on a trajectory across the life span. An abnormal fetal …

About three days after a human egg is fertilized, it passes through the fallopian tunnel and
reaches the uterus, where it spends about four days floating in the uterus's fluids, after which …

Ethanol is a well-established developmental toxicant; however, the mechanism (s) of this
toxicity remains unclear. Zebrafish are becoming an important model system for the …

Ethanol is a well-established developmental toxicant; however, the molecular and cellular
mechanism (s) of toxicity remains unclear. It has been suggested that ethanol metabolism …

To pursue the hypothesis that differences in the regulatory region ofCYP2E1are partially
responsible for the intersubject variation inin vivoCYP2E1 activity, restriction enzyme …

The dominant neurochemicals involved in encoding sensory information are the amino acid
neurotransmitters, glutamate, γ-aminobutyrate (GABA) and glycine which mediate fast point …

Ethanol induces oxidative stress in cultured fetal rat cortical neurons and this is followed by
apoptotic death, which can be prevented by normalization of cell content of reduced …

Ethanol is teratogenic to many vertebrates. We are utilizing zebrafish as a model system to
determine whether there is an association between ethanol metabolism and ethanol …