Reconstruction of the Austronesian diaspora in the era of genomics

GK Chambers, HA Edinur - Human Biology, 2020 - muse.jhu.edu
The Austronesian Diaspora is a 5,000-year account of how a small group of Taiwanese
farmers expanded to occupy territories reaching halfway around the world. Reconstructing …

Pharmacogenetics of common SNP affecting drug metabolizing enzymes: comparison of allele frequencies between European and Malaysian/Singaporean

NS Bakar - Drug metabolism and personalized therapy, 2021 - degruyter.com
Compared to Europe, data on genetic variation in genes transcribing drug metabolizing
enzymes among Asian is limited due to ethnic diversity. Here we compare frequencies for …

Exploring public genomics data for population pharmacogenomics

K Lakiotaki, A Kanterakis, E Kartsaki, T Katsila… - PloS one, 2017 - journals.plos.org
Racial and ethnic differences in drug responses are now well studied and documented.
Pharmacogenomics research seeks to unravel the genetic underpinnings of inter-individual …

Introducing the first whole genomes of nationals from the United Arab Emirates

HS AlSafar, M Al-Ali, GD Elbait, MH Al-Maini, D Ruta… - Scientific Reports, 2019 - nature.com
Abstract Whole Genome Sequencing (WGS) provides an in depth description of genome
variation. In the era of large-scale population genome projects, the assembly of ethnic …

Pharmacogenomics based practice in Malaysia: the attitude, knowledge and adoption by the healthcare professionals

Z Bannur, S Bahaman, MZ Salleh… - IIUM Medical Journal …, 2014 - journals.iium.edu.my
Introduction: Knowledge, attitude as well as adoption of pharmacogenomics in clinical
practice among the pharmacists and physicians in Malaysia have not been reported. This …

Genomic structure of the native inhabitants of Peninsular Malaysia and North Borneo suggests complex human population history in Southeast Asia

CW Yew, D Lu, L Deng, LP Wong, RTH Ong, Y Lu… - Human genetics, 2018 - Springer
Southeast Asia (SEA) is enriched with a complex history of peopling. Malaysia, which is
located at the crossroads of SEA, has been recognized as one of the hubs for early human …

Content analysis of informed consent for whole genome sequencing offered by direct‐to‐consumer genetic testing companies

E Niemiec, P Borry, W Pinxten, HC Howard - Human mutation, 2016 - Wiley Online Library
Whole exome sequencing (WES) and whole genome sequencing (WGS) have become
increasingly available in the research and clinical settings and are now also being offered …

Genetic epidemiology of pharmacogenetic variants in South East Asian Malays using whole-genome sequences

A Sivadas, MZ Salleh, LK Teh, V Scaria - The Pharmacogenomics …, 2017 - nature.com
Expanding the scope of pharmacogenomic research by including multiple global
populations is integral to building robust evidence for its clinical translation. Deep whole …

Pharmacogenomics-based practice in North Cyprus: its adoption by pharmacists and their attitudes and knowledge

L Alsaloumi, A Abdi, Ö Tosun, B Başgut - International journal of clinical …, 2019 - Springer
Background Pharmacogenomics is a branch of biotechnological science integrating
medicine, pharmacology, and genomics techniques. Moreover, it focuses on creating drug …

Pharmacogenetic landscape of clopidogrel in north Indians suggest distinct interpopulation differences in allele frequencies

AK Giri, NM Khan, INDICO, A Basu, N Tandon… - …, 2014 - Taylor & Francis
Aim: Clopidogrel, a widely used antiplatelet drug, exhibits high interindividual variability;
more than 80% of which could be explained by genetic polymorphisms. We built an allele …