Evidence from human and animal studies suggests that high-energy diets impair cognitive
function. However, the conditions for such impairments are unclear as studies have differed …

The incidence of metabolic disorders, as well as of neurodegenerative diseases—mainly the
sporadic forms of Alzheimer's and Parkinson's disease—are increasing worldwide. Notably …

Background: Evidence has revealed an association between familial hypercholesterolemia
and cognitive impairment. In this regard, a connection between cognitive deficits and …

The presence of insoluble aggregates of amyloid β (Aβ) in the form of neuritic plaques (NPs)
is one of the main features that define Alzheimer's disease. Studies have suggested that the …

Familial hypercholesterolemia (FH) is a metabolic condition caused mainly by a mutation in
the low-density lipoprotein (LDL) receptor gene (LDLR), which is highly prevalent in the …

The low-density-lipoprotein receptor (LDLr) removes low-density lipoprotein (LDL), an
endovascular transporter that carries cholesterol from the bloodstream to peripheral tissues …

There exists an intricate relationship between hypercholesterolemia (elevated plasma
cholesterol) and brain functions. The present study aims to understand the impact of …

The current study aimed to develop alendronate (ALN)-loaded chitosan nanoparticles (CS-
ALN-NPs) for brain delivery via intranasal route. These CS-ALN-NPs reduced the peripheral …

Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized
by a persistent impairment of social skills, including aspects of perception, interpretation …

Familial hypercholesterolemia (FH) is caused by mutations in the gene that encodes the low‐
density lipoprotein (LDL) receptor, which leads to an excessive increase in plasma LDL …