Periodontitis and implant complications in diabetes

L Nibali, N Gkranias, G Mainas… - Periodontology 2000, 2022 - Wiley Online Library
Epidemiologic evidence indicates that periodontitis is more frequent in patients with
uncontrolled diabetes mellitus than in healthy controls, suggesting that it could be …

The case for periodontitis in the pathogenesis of rheumatoid arthritis

J Potempa, P Mydel, J Koziel - Nature Reviews Rheumatology, 2017 - nature.com
Rheumatoid arthritis (RA), an autoimmune disease that affects∼ 1% of the human
population, is driven by autoantibodies that target modified self-epitopes, whereas∼ 11% of …

Aggregatibacter actinomycetemcomitans–induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis

MF Konig, L Abusleme, J Reinholdt… - Science translational …, 2016 - science.org
A bacterial etiology of rheumatoid arthritis (RA) has been suspected since the beginnings of
modern germ theory. Recent studies implicate mucosal surfaces as sites of disease …

Periodontitis and rheumatoid arthritis: What have we learned about their connection and their treatment?

J González‐Febles, M Sanz - Periodontology 2000, 2021 - Wiley Online Library
Rheumatoid arthritis and periodontitis are chronic inflammatory diseases defined
respectively by the destruction of the articular cartilage and tooth‐supporting periodontal …

The multifactorial role of neutrophils in rheumatoid arthritis

HL Wright, RJ Moots, SW Edwards - Nature Reviews Rheumatology, 2014 - nature.com
Of all cells implicated in the pathology of rheumatoid arthritis (RA), neutrophils possess the
greatest cytotoxic potential, owing to their ability to release degradative enzymes and …

The pre-clinical phase of rheumatoid arthritis: from risk factors to prevention of arthritis

N Petrovská, K Prajzlerová, J Vencovský, L Šenolt… - Autoimmunity …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease considered as a multistep
process spanning from the interaction of genetic (eg, shared epitope or non-HLA loci) …

[HTML][HTML] Immune modulation of some autoimmune diseases: the critical role of macrophages and neutrophils in the innate and adaptive immunity

KC Navegantes, R de Souza Gomes… - Journal of translational …, 2017 - Springer
Macrophages and neutrophils are key components involved in the regulation of numerous
chronic inflammatory diseases, infectious disorders, and especially certain autoimmune …

[HTML][HTML] Host–microbiota interactions in rheumatoid arthritis

Y Maeda, K Takeda - Experimental & Molecular Medicine, 2019 - nature.com
The gut microbiota has been proposed to be an important environmental factor in the
development of rheumatoid arthritis (RA). Here, we review a growing body of evidence from …

[PDF][PDF] Periodontitis and Porphyromonas gingivalis in Patients With Rheumatoid Arthritis

TR Mikuls, JB Payne, F Yu, GM Thiele… - Arthritis & …, 2014 - Wiley Online Library
Objective To examine the degree to which shared risk factors explain the relationship of
periodontitis (PD) to rheumatoid arthritis (RA) and to determine the associations of PD and …

[HTML][HTML] Host and bacterial factors linking periodontitis and rheumatoid arthritis

A Krutyhołowa, K Strzelec, A Dziedzic… - Frontiers in …, 2022 - frontiersin.org
Observations from numerous clinical, epidemiological and serological studies link
periodontitis with severity and progression of rheumatoid arthritis. The strong association is …