Interpretable deep learning uncovers cellular properties in label-free live cell images that are predictive of highly metastatic melanoma
Deep learning has emerged as the technique of choice for identifying hidden patterns in cell
imaging data but is often criticized as" black box." Here, we employ a generative neural …
imaging data but is often criticized as" black box." Here, we employ a generative neural …
Five priority areas for improving medications development for alcohol use disorder and promoting their routine use in clinical practice.
RZ Litten, DE Falk, ML Ryan, J Fertig… - Alcoholism: Clinical and …, 2020 - psycnet.apa.org
The article discusses about the priority areas for improving medications development for
alcohol use disorder and promoting their routine use in clinical practice. During the past 25 …
alcohol use disorder and promoting their routine use in clinical practice. During the past 25 …
Computational approaches for high‐throughput single‐cell data analysis
H Todorov, Y Saeys - The FEBS journal, 2019 - Wiley Online Library
During the past decade, the number of novel technologies to interrogate biological systems
at the single‐cell level has skyrocketed. Numerous approaches for measuring the proteome …
at the single‐cell level has skyrocketed. Numerous approaches for measuring the proteome …
Predicting chemical-induced liver toxicity using high-content imaging phenotypes and chemical descriptors: a random forest approach
Hepatotoxicity is a major reason for the withdrawal or discontinuation of drugs from clinical
trials. Thus, better tools are needed to filter potential hepatotoxic drugs early in drug …
trials. Thus, better tools are needed to filter potential hepatotoxic drugs early in drug …
New software for automated cilia detection in cells (ACDC)
Background Primary cilia frequency and length are key metrics in studies of ciliogenesis and
ciliopathies. Typically, quantitative cilia analysis is done manually, which is very time …
ciliopathies. Typically, quantitative cilia analysis is done manually, which is very time …
Quantitative cell imaging approaches to metastatic state profiling
AJ Nevarez, N Hao - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Genetic heterogeneity of metastatic dissemination has proven challenging to identify
exploitable markers of metastasis; this bottom-up approach has caused a stalemate …
exploitable markers of metastasis; this bottom-up approach has caused a stalemate …
Interpretable deep learning of label-free live cell images uncovers functional hallmarks of highly-metastatic melanoma
Deep convolutional neural networks have emerged as a powerful technique to identify
hidden patterns in complex cell imaging data. However, these machine learning techniques …
hidden patterns in complex cell imaging data. However, these machine learning techniques …
Novel image analysis tool for rapid screening of cell morphology in preclinical animal models of disease
The field of cell biology has seen major advances in both cellular imaging modalities and
the development of automated image analysis platforms that increase rigor, reproducibility …
the development of automated image analysis platforms that increase rigor, reproducibility …
Новая компьютерная программа автоматизированного анализа движения цилиарного эпителия респираторного тракта для диагностики первичной …
ТА Киян, CА Смирнихина, АГ Демченко… - …, 2024 - journal.pulmonology.ru
Аннотация Первичная цилиарная дискинезия (ПЦД)–редкое наследственное
заболевание из группы цилиопатий, при котором нарушены структура и подвижность …
заболевание из группы цилиопатий, при котором нарушены структура и подвижность …