An ever-increasing demand for novel antimicrobials to treat life-threatening infections
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …

Metabolic engineers endeavor to create a bio-based manufacturing industry using microbes
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …

Bolstered by recent advances in bioinformatics, genetics, and enzyme engineering, the field
of chemoenzymatic synthesis has enjoyed a rapid increase in popularity and utility. This …

Competitive sustainable production in industry demands new and better biocatalysts,
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …

Streptomyces has a strong capability for producing a large number of bioactive natural
products and remains invaluable as a source for the discovery of novel drug leads. Although …

Natural products (NPs) are critical sources of drug molecules for decades. About two-thirds
of natural antibiotics are produced by Streptomyces. Streptomyces have a large number of …

For over seven decades, bacteria served as a valuable source of bioactive natural products
some of which were eventually developed into drugs to treat infections, cancer and immune …

Pathway optimization plays an important role in fine-tuning metabolic pathways. In most
conditions, more than three genes are involved in the biosynthesis pathway of a specific …

Marine environments are largely unexplored and can be a source of new molecules for the
treatment of many diseases such as malaria, cancer, tuberculosis, HIV etc. The Marine …

Covering: 2000 to 2016 The labor-intensive process of microbial natural product discovery is
contingent upon identifying discrete secondary metabolites of interest within complex …