Autophagy and the unfolded protein response shape the non-alcoholic fatty liver landscape: decoding the labyrinth

Z Dashti, Z Yousefi, P Kiani, M Taghizadeh, MH Maleki… - Metabolism, 2024 - Elsevier
The incidence of nonalcoholic fatty liver disease (NAFLD) is on the rise, mirroring a global
surge in diabetes and metabolic syndrome, as its major leading causes. NAFLD represents …

Frontiers of Collaboration between Primary Care and Specialists in the Management of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Review

K Nagai, K Nagai, M Iwaki, T Kobayashi, A Nogami… - Life, 2023 - mdpi.com
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as
nonalcoholic fatty liver disease (NAFLD), is the most common liver disease. It has a rapidly …

Advancing Osteoporotic Bone Regeneration Through Tailored Tea Polyphenols Functionalized Micro‐/Nano‐Hydroxyapatite Bioceramics

R Zhao, H Qian, X Zhu, X Zhang… - Advanced Functional …, 2024 - Wiley Online Library
Efforts to develop advanced bone substitutes for effective bone regeneration in substantial
defects have led to the fabrication of tissue‐engineered scaffolds. These scaffolds, featuring …

Endoplasmic Reticulum Stress Induces Vasodilation in Liver Vessels That Is Not Mediated by Unfolded Protein Response

S Zavadskis, A Shiganyan, A Müllebner… - International Journal of …, 2024 - mdpi.com
There is a growing body of evidence that ER stress and the unfolded protein response
(UPR) play a key role in numerous diseases. Impaired liver perfusion and ER stress often …

Long non‐coding RNA‐mediated modulation of endoplasmic reticulum stress under pathological conditions

YC Çiftçi, Y Yurtsever, B Akgül - Journal of Cellular and …, 2024 - Wiley Online Library
Endoplasmic reticulum (ER) stress, which ensues from an overwhelming protein folding
capacity, activates the unfolded protein response (UPR) in an effort to restore cellular …

[HTML][HTML] Endoplasmic Reticulum Stress Signaling in the Regulation of Hepatic Pathological Responses

A Baral - Stresses, 2024 - mdpi.com
The endoplasmic reticulum (ER) is a vital cell organelle that is primarily involved in the
processes of protein folding, maintenance of intracellular calcium storage and lipid synthesis …

Common Perk Variants Alter Stress Resilience

S Ghura - 2023 - search.proquest.com
Abstract EIF2AK3 encodes PKR-like endoplasmic reticulum (ER) kinase (PERK), which
regulates ER stress response and plays a crucial role in deciding the cell's commitment to …