Diabetic gastrointestinal motility disorders and the role of enteric nervous system: current status and future directions

SS Yarandi, S Srinivasan - Neurogastroenterology & Motility, 2014 - Wiley Online Library
Background Gastrointestinal manifestations of diabetes are common and a source of
significant discomfort and disability. Diabetes affects almost every part of gastrointestinal …

Diabetes and the enteric nervous system

B Chandrasekharan… - Neurogastroenterology & …, 2007 - Wiley Online Library
Diabetes is associated with several changes in gastrointestinal (GI) motility and associated
symptoms such as nausea, bloating, abdominal pain, diarrhoea and constipation. The …

Interactions between the microbiota and enteric nervous system during gut-brain disorders

S Fried, E Wemelle, PD Cani, C Knauf - Neuropharmacology, 2021 - Elsevier
For the last 20 years, researchers have focused their intention on the impact of gut
microbiota in healthy and pathological conditions. This year (2021), more than 25,000 …

GDNF rescues hyperglycemia-induced diabetic enteric neuropathy through activation of the PI3K/Akt pathway

M Anitha, C Gondha, R Sutliff… - The Journal of …, 2006 - Am Soc Clin Investig
Diabetes can result in loss of enteric neurons and subsequent gastrointestinal
complications. The mechanism of enteric neuronal loss in diabetes is not known. We …

Diabetic enteropathy: from molecule to mechanism‐based treatment

T Meldgaard, SS Olesen, AD Farmer… - Journal of diabetes …, 2018 - Wiley Online Library
The incidence of the micro‐and macrovascular complications of diabetes is rising, mirroring
the increase in the worldwide prevalence. Arguably, the most common microvascular …

Pathogenesis and management of diabetic gastroparesis: An updated clinically oriented review

S Uppaluri, MA Jain, H Ali, J Shingala, D Amin… - Diabetes & Metabolic …, 2024 - Elsevier
Background and aims Diabetic gastroparesis (DGp) is a common and preventable
complication of uncontrolled diabetes mellitus (DM) and significantly affects the quality of life …

Diabetic autonomic neuropathy: evidence for apoptosis in situ in the rat

C Guo, A Quobatari, Y Shangguan… - …, 2004 - Wiley Online Library
We examined the hypothesis that activation of the apoptosis cascade occurs relatively early
in diabetes mellitus affecting three distinct neuronal populations that are involved in …

Histomorphometry changes and decreased reactivity to angiotensin II in the ileum and colon of streptozotocin-induced diabetic rats

M Esteves-Monteiro, D Menezes-Pinto… - International Journal of …, 2022 - mdpi.com
Diabetes mellitus (DM) is a chronic progressive metabolic disorder associated with several
gastrointestinal complications, affecting up to 75% of patients. Knowing that Angiotensin II …

Morphoquantitative effects of acute diabetes on the myenteric neurons of the proximal colon of adult rats

MMDP Furlan, SL Molinari… - Arquivos de neuro …, 2002 - SciELO Brasil
The effects of acute diabetes on the density and size of the myenteric neurons of the
proximal colon of adult rats were investigated. The injection of streptozotocin was followed …

[HTML][HTML] Gastrointestinal motility and glycemic control in diabetes: the chicken and the egg revisited?

CK Rayner, M Horowitz - The Journal of clinical …, 2006 - Am Soc Clin Investig
Upper gastrointestinal dysfunction occurs frequently in diabetes and potentially contributes
to both abdominal symptoms and impaired glycemic control; conversely, variations in blood …