[HTML][HTML] A review of inactivated COVID-19 vaccine development in China: focusing on safety and efficacy in special populations

L Hu, J Sun, Y Wang, D Tan, Z Cao, L Gao, Y Guan… - Vaccines, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has been widespread globally, and …

[HTML][HTML] Pathophysiological, immunological, and inflammatory features of long COVID

K Bohmwald, B Diethelm-Varela… - Frontiers in …, 2024 - frontiersin.org
The COVID-19 pandemic continues to cause severe global disruption, resulting in significant
excess mortality, overwhelming healthcare systems, and imposing substantial social and …

[HTML][HTML] COVID-19 vaccination in pediatrics: was it valuable and successful?

MA Raslan, SA Raslan, EM Shehata, AS Mahmoud… - Vaccines, 2023 - mdpi.com
Background: The mass vaccination of children against coronavirus 2019 disease (COVID-
19) has been frequently debated. The risk–benefit assessment of COVID-19 vaccination …

Real-world effectiveness of primary series and booster doses of inactivated coronavirus disease 2019 vaccine against Omicron BA. 2 variant infection in China: a …

L Tang, FZ Wang, LE Rodewald… - The Journal of …, 2023 - academic.oup.com
Background China has been using inactivated coronavirus disease 2019 (COVID-19)
vaccines as primary series and booster doses to protect the population from severe to fatal …

The MegaPool Approach to Characterize Adaptive CD4+ and CD8+ T Cell Responses

R da Silva Antunes, D Weiskopf, J Sidney… - Current …, 2023 - Wiley Online Library
Epitopes recognized by T cells are a collection of short peptide fragments derived from
specific antigens or proteins. Immunological research to study T cell responses is hindered …

[HTML][HTML] Different Safety Pattern of an Inactivated SARS-CoV-2 Vaccine (CoronaVac®) According to Age Group in a Pediatric Population from 3 to 17 Years Old, in an …

N Le Corre, K Abarca, P Astudillo, M Potin, S López… - Vaccines, 2023 - mdpi.com
During the COVID-19 pandemic, the importance of vaccinating children against SARS-CoV-
2 was rapidly established. This study describes the safety of CoronaVac® in children and …

[HTML][HTML] Comparative Immune Response after Vaccination with SOBERANA® 02 and SOBERANA® plus Heterologous Scheme and Natural Infection in Young …

R Pérez-Nicado, C Massa, LM Rodríguez-Noda… - Vaccines, 2023 - mdpi.com
(1) Background: In children, SARS-CoV-2 infection is mostly accompanied by mild COVID-
19 symptoms. However, multisystem inflammatory syndrome (MIS-C) and long-term …

Immune responses during COVID-19 breakthrough cases in vaccinated children and adolescents

D Rivera-Pérez, C Méndez, B Diethelm-Varela… - Frontiers in …, 2024 - frontiersin.org
Background Vaccine effectiveness against SARS-CoV-2 infection has been somewhat
limited due to the widespread dissemination of the Omicron variant, its subvariants, and the …

New insights into the pathogenesis of SARS-CoV-2 during and after the COVID-19 pandemic

JJ Carvajal, V García-Castillo, SV Cuellar… - Frontiers in …, 2024 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
respiratory distress condition known as COVID-19. This disease broadly affects several …

Preclinical immunogenicity risk assessment of biotherapeutics using CD4 T cell assays

RE Walsh, A Nix, C Ackaert, A Mazy… - Frontiers in …, 2024 - frontiersin.org
T-cell dependent antibody responses to biotherapeutics remain a challenge to the optimal
clinical application of biotherapeutics because of their capacity to impair drug efficacy and …