The function of antibodies (Abs) involves specific binding to antigens (Ags) and activation of
other components of the immune system to fight pathogens. The six hypervariable loops …

The year 2004 represents a milestone for the biosensor research community: in this year,
over 1000 articles were published describing experiments performed using commercially …

Mounting evidence indicates that grouping of chronic lymphocytic leukemia (CLL) into
distinct subsets with stereotyped BCRs is functionally and prognostically relevant. However …

Abstract abYsis is a web-based antibody research system that includes an integrated
database of antibody sequence and structure data. The system can be interrogated in …

We examined 807 productive IGHV-IGHD-IGHJ gene rearrangements from mantle cell
lymphoma (MCL) cases, by far the largest series to date. The IGHV gene repertoire was …

Immunoglobulin kappa (IGK) and immunoglobulin lambda (IGL) light chain repertoire was
analyzed in 276 chronic lymphocytic leukemia (CLL) cases and compared with the relevant …

We performed an immunogenetic analysis of 345 IGHV–IGHD–IGHJ rearrangements from
337 cases with primary splenic small B-cell lymphomas of marginal-zone origin. Three …

Chronic lymphocytic leukemia (CLL) is uniquely characterized by the existence of subsets of
cases with quasi-identical,'stereotyped'B-cell receptors (BCRs). Herein we investigate this …

General protein–protein interfaces are known to be enriched, compared with other surface
patches, with amino acids that can form stabilizing interactions. However, several studies …

Motivation: An ever-increasing body of evidence supports the importance of B cell receptor
immunoglobulin (BcR IG) sequence restriction, alias stereotypy, in chronic lymphocytic …