Liquid-infused surfaces: a review of theory, design, and applications

M Villegas, Y Zhang, N Abu Jarad, L Soleymani… - Acs Nano, 2019 - ACS Publications
Due to inspiration from the Nepenthes pitcher plant, a frontier of devices has emerged with
unmatched capabilities. Liquid-infused surfaces (LISs), particularly known for their liquid …

Prosthetic heart valve thrombosis

GD Dangas, JI Weitz, G Giustino, R Makkar… - Journal of the American …, 2016 - jacc.org
Although surgery was the mainstay of treatment for valvular heart disease, transcatheter
valve therapies have grown exponentially over the past decade. Two types of artificial heart …

Medical device‐induced thrombosis: what causes it and how can we prevent it?

IH Jaffer, JC Fredenburgh, J Hirsh… - Journal of Thrombosis …, 2015 - Wiley Online Library
Blood‐contacting medical devices, such as vascular grafts, stents, heart valves, and
catheters, are often used to treat cardiovascular diseases. Thrombus formation is a common …

[HTML][HTML] The contact activation and kallikrein/kinin systems: pathophysiologic and physiologic activities

AH Schmaier - Journal of Thrombosis and Haemostasis, 2016 - Elsevier
The contact activation system (CAS) and kallikrein/kinin system (KKS) are older recognized
biochemical pathways that include several proteins that skirt the fringes of the blood …

[HTML][HTML] The blood compatibility challenge. Part 1: Blood-contacting medical devices: The scope of the problem

IH Jaffer, JI Weitz - Acta biomaterialia, 2019 - Elsevier
Blood-contacting medical devices are an integral part of modern medicine. Such devices
may be used for only a few hours or may be implanted for life. Despite advances in …

Current understanding of how extracorporeal membrane oxygenators activate haemostasis and other blood components

AJ Doyle, BJ Hunt - Frontiers in medicine, 2018 - frontiersin.org
Extracorporeal membrane oxygenators are used in critical care for the management of
severe respiratory and cardiac failure. Activation of the coagulation system is initiated by the …

Blood compatible materials: state of the art

X Liu, L Yuan, D Li, Z Tang, Y Wang, G Chen… - Journal of Materials …, 2014 - pubs.rsc.org
Devices that function in contact with blood are ubiquitous in clinical medicine and
biotechnology. These devices include vascular grafts, coronary stents, heart valves …

Single and multi-functional coating strategies for enhancing the biocompatibility and tissue integration of blood-contacting medical implants

M Badv, F Bayat, JI Weitz, TF Didar - Biomaterials, 2020 - Elsevier
Device-associated clot formation and poor tissue integration are ongoing problems with
permanent and temporary implantable medical devices. These complications lead to …

Antithrombotic agents: new directions in antithrombotic therapy

NC Chan, JI Weitz - Circulation research, 2019 - Am Heart Assoc
Recent advances in our understanding of the contribution of thrombin generation to arterial
thrombosis and the role of platelets in venous thrombosis have prompted new treatment …

Lubricant-infused surfaces with built-in functional biomolecules exhibit simultaneous repellency and tunable cell adhesion

M Badv, SM Imani, JI Weitz, TF Didar - ACS nano, 2018 - ACS Publications
Lubricant-infused omniphobic surfaces have exhibited outstanding effectiveness in
inhibiting nonspecific adhesion and attenuating superimposed clot formation compared with …