Catalytic functionalization of indoles in a new dimension

M Bandini, A Eichholzer - Angewandte Chemie International …, 2009 - Wiley Online Library
Abstract 140 Years ago Adolf von Baeyer proposed the structure of a heteroaromatic
compound which revolutionized organic and medical chemistry: indole. After more than a …

Strategies for the asymmetric functionalization of indoles: an update

R Dalpozzo - Chemical Society Reviews, 2015 - pubs.rsc.org
During the past four years, the research of new synthetic methodologies for the rapid
construction of enantiomerically pure substituted indole has had a fruitful and important …

Iminium catalysis

A Erkkilä, I Majander, PM Pihko - Chemical Reviews, 2007 - ACS Publications
This review covers reactions where iminium ions are likely to be active intermediates in the
catalytic cycle. The focus of the review is on synthetically useful protocols and smallmolecule …

Asymmetric aminocatalysis—gold rush in organic chemistry

P Melchiorre, M Marigo, A Carlone… - Angewandte Chemie …, 2008 - Wiley Online Library
Catalysis with chiral secondary amines (asymmetric aminocatalysis) has become a well‐
established and powerful synthetic tool for the chemo‐and enantioselective functionalization …

Organocatalytic carbon–sulfur bond-forming reactions

P Chauhan, S Mahajan, D Enders - Chemical reviews, 2014 - ACS Publications
Carbon− heteroatom bond formations are very important reactions in organic synthesis and
have attracted the interest of many synthetic organic chemists, leading them to develop new …

Cinchona‐based primary amine catalysis in the asymmetric functionalization of carbonyl compounds

P Melchiorre - Angewandte Chemie International Edition, 2012 - Wiley Online Library
Asymmetric aminocatalysis exploits the potential of chiral primary and secondary amines to
catalyze asymmetric reactions. It has greatly simplified the functionalization of carbonyl …

Organocatalytic strategies for the asymmetric functionalization of indoles

G Bartoli, G Bencivenni, R Dalpozzo - Chemical Society Reviews, 2010 - pubs.rsc.org
The desire for new synthetic methodologies for the rapid construction of enantiomerically
pure substituted indole has been a fruitful driving force for chemical research in the last few …

Catalytic Asymmetric Friedel− Crafts Alkylation Reactions Copper Showed the Way

TB Poulsen, KA Jørgensen - Chemical Reviews, 2008 - ACS Publications
Charles Friedel (1832-1899) started a dual scientific career and spent several years of
activities divided between mineralogy at Ecole des Mines and chemical research. 1 The …

Green chemistry meets asymmetric organocatalysis: a critical overview on catalysts synthesis

A Antenucci, S Dughera, P Renzi - ChemSusChem, 2021 - Wiley Online Library
Can green chemistry be the right reading key to let organocatalyst design take a step
forward towards sustainable catalysis? What if the intriguing chemistry promoted by more …

Cinchona alkaloids in asymmetric organocatalysis

T Marcelli, H Hiemstra - Synthesis, 2010 - thieme-connect.com
This article reviews the applications of cinchona alkaloids as asymmetric catalysts. In the last
few years, characterized by the resurgence of interest in asymmetric organocatalysis …