As human space exploration advances to establish a permanent presence beyond the Low
Earth Orbit (LEO) with NASA's Artemis mission, researchers are striving to understand and …

As NASA prepares for the first manned mission to Mars in the next 20 years, close attention
has been placed on the cognitive welfare of astronauts, who will likely endure extended …

The Mars mission will result in an inevitable exposure to cosmic radiation that has been
shown to cause cognitive impairments in rodent models, and possibly in astronauts …

Cranial irradiation is the main therapeutic treatment for primary and metastatic malignancies
in the brain. However, cranial radiation therapy produces long-term impairment in memory …

Dendritic spine development is crucial for the establishment of excitatory synaptic
connectivity and functional neural circuits. Alterations in spine morphology and density have …

Abstract Space travel will expose people to high-energy, heavy particle radiation, and the
cognitive deficits induced by this exposure are not well understood. To investigate the short …

Abstract Space and time are both essential features of episodic memory, for which the
hippocampus is critical (Howard & Eichenbaum, 2015). Spatial tasks have been used …

High‐energy charged particles are considered particularly hazardous components of the
space radiation environment. Such particles include fully ionized energetic nuclei of helium …

Ovarian steroids modulate the neuronal structure and function during the estrous cycle,
contrasting peak effects during the proestrus cycle and low effects during the metestrus …

Cognitive dysfunction is the most common form of radiation-induced brain injury. TDP-43 is
known to be associated with hippocampal degeneration and cognitive dysfunction, in this …