Mobile genetic elements in Acinetobacter antibiotic‐resistance acquisition and dissemination

HR Noel, JR Petrey, LD Palmer - … of the New York Academy of …, 2022 - Wiley Online Library
Pathogenic Acinetobacter species, most notably Acinetobacter baumannii, are a significant
cause of healthcare‐associated infections worldwide. Acinetobacter infections are of …

Acinetobacter metabolism in infection and antimicrobial resistance

X Ren, LD Palmer - Infection and Immunity, 2023 - Am Soc Microbiol
Acinetobacter infections have high rates of mortality due to an increasing incidence of
infections by multidrug-resistant (MDR) and extensively-drug-resistant (XDR) strains …

Combined exposure to non-antibiotic pharmaceutics and antibiotics in the gut synergistically promote the development of multi-drug-resistance in Escherichia coli

D Shi, H Hao, Z Wei, D Yang, J Yin, H Li, Z Chen… - Gut …, 2022 - Taylor & Francis
The gut microbiota represents an important reservoir of antibiotic-resistant bacteria (ARB),
which poses a significant threat to public health. However, little is known about the …

Identification of two variants of Acinetobacter baumannii strain ATCC 17978 with distinct genotypes and phenotypes

CDM Wijers, L Pham, S Menon, KL Boyd… - Infection and …, 2021 - Am Soc Microbiol
Acinetobacter baumannii is a nosocomial pathogen that exhibits substantial genomic
plasticity. Here, the identification of two variants of A. baumannii ATCC 17978 that differ …

[HTML][HTML] Deficient Pseudomonas aeruginosa in MlaA/VacJ outer membrane lipoprotein shows decrease in rhamnolipids secretion, motility, and biofilm formation, and …

M Kaur, JM Buyck, F Goormaghtigh, JL Decout… - Research in …, 2023 - Elsevier
Pseudomonas aeruginosa, a Gram-negative bacterium that causes severe hospital acquired
infections poses threat by its ability for adaptation to various growth modes and …

Genetic synergy between Acinetobacter baumannii undecaprenyl phosphate biosynthesis and the Mla system impacts cell envelope and antimicrobial resistance

HR Noel, S Keerthi, X Ren, JD Winkelman… - Mbio, 2024 - Am Soc Microbiol
Acinetobacter baumannii is a Gram-negative bacterial pathogen that poses a major health
concern due to increasing multidrug resistance. The Gram-negative cell envelope is a key …

[HTML][HTML] Zinc glycinate alleviates LPS-induced inflammation and intestinal barrier disruption in chicken embryos by regulating zinc homeostasis and TLR4/NF-κB …

C Xiao, L Comer, X Pan, N Everaert, M Schroyen… - Ecotoxicology and …, 2024 - Elsevier
The effect of an immune challenge induced by a lipopolysaccharide (LPS) exposure on
systemic zinc homeostasis and the modulation of zinc glycinate (Zn-Gly) was investigated …

The metabolic slowdown caused by the deletion of pspA accelerates protein aggregation during stationary phase facilitating antibiotic persistence

Y Li, X Chen, W Zhang, K Fang, J Tian… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Entering a dormant state is a prevailing mechanism used by bacterial cells to transiently
evade antibiotic attacks and become persisters. The dynamic progression of bacterial …

Gram-negative bacteria act as a reservoir for aminoglycoside antibiotics that interact with host factors to enhance bacterial killing in a mouse model of pneumonia

CDM Wijers, L Pham, MV Douglass, EP Skaar… - FEMS …, 2022 - academic.oup.com
In vitro exposure of multiple Gram-negative bacteria to an aminoglycoside (AG) antibiotic
has previously been demonstrated to result in bacterial alterations that interact with host …

Klebsiella pneumoniae DedA family proteins have redundant roles in divalent cation homeostasis and resistance to phagocytosis

V Tiwari, A Sharma, R Braga, E Garcia… - Microbiology …, 2024 - Am Soc Microbiol
The DedA superfamily is a highly conserved family of membrane proteins. Deletion of
Escherichia coli yqjA and yghB, encoding related DedA family proteins, results in sensitivity …